OCT in animal models

Due to their accessibility, animal models are playing a major role in understanding some of the underlying causes of glaucoma. Optical Coherence Tomography (OCT) has been used extensively in these animal models giving us the advantage of longitudinal in-vivo assessments of the natural history of this disease. Outer retina involvement has recently been demonstrated in-vivo in experimental glaucoma. OCT segmentation software are now available as an aid for understanding the involvement of retinal layers other than the RNFL. Retinal blood flow is also currently under investigation in experimental glaucoma using ultra high resolution OCT. Furthermore, investigations of the irido-corneal angle configuration and its structural modifications in response to anti glaucoma drugs have also been conducted in experimental models using anterior segment OCT. The talk will discuss the utility of OCT in animal models in Glaucoma.