Volume 3, Issue 4 pp. 299-302

Argatroban Anticoagulation for Cardiac Surgery with Cardiopulmonary Bypass in an Infant with Double Outlet Right Ventricle and a History of Heparin-induced Thrombocytopenia

Michael L. Ciccolo MD

Michael L. Ciccolo MD

Cardiothoracic Surgery, Cardiovascular Surgical Associates,

University of Nevada School of Medicine,

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Jonathan Bernstein MD

Jonathan Bernstein MD

Pediatric Hematology and Oncology, Childrens Center for Cancer and Blood Disease,

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Juan C. Collazos MD

Juan C. Collazos MD

Children's Heart Center, and

Department of Cardiology and Pediatrics,

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Ruben J. Acherman MD

Ruben J. Acherman MD

Children's Heart Center, and

Department of Cardiology and Pediatrics,

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Humberto Restrepo MD, MPH

Humberto Restrepo MD, MPH

Children's Heart Center, and

Department of Cardiology and Pediatrics,

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James M. Winters CCP

James M. Winters CCP

Clinical Technician Associates, Las Vegas, Nev, USA

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Justin Krueger CCP

Justin Krueger CCP

Clinical Technician Associates, Las Vegas, Nev, USA

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William N. Evans MD

Corresponding Author

William N. Evans MD

Children's Heart Center, and

Department of Cardiology and Pediatrics,

William N. Evans, MD, Children's Heart Center, 3006 S. Maryland Pkwy., Suite 690, Las Vegas, NV 89109, USA. Tel: (+1) 702-732-1290; Fax: (+1) 702-732-1385; E-mail: [email protected]Search for more papers by this author
First published: 22 July 2008
Citations: 8

ABSTRACT

Heparin-induced thrombocytopenia (HIT) is a life-threatening complication of heparin therapy. Anticoagulation in pediatric patients with HIT is challenging as there are no approved heparin substitutes. We report the use of the anticoagulant argatroban for cardiac surgery with cardiopulmonary bypass in an infant with double outlet right ventricle and a history of HIT.

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