Neuroactive Steroids Protect Retinal Tissue through σ1 Receptors
Claudio Bucolo,
Claudio Bucolo
Department of Experimental and Clinical Pharmacology, School of Medicine, University of Catania, Catania, Italy
Search for more papers by this author Filippo Drago,
Filippo Drago
Department of Experimental and Clinical Pharmacology, School of Medicine, University of Catania, Catania, Italy
Search for more papers by this author
Claudio Bucolo,
Claudio Bucolo
Department of Experimental and Clinical Pharmacology, School of Medicine, University of Catania, Catania, Italy
Search for more papers by this author Filippo Drago,
Filippo Drago
Department of Experimental and Clinical Pharmacology, School of Medicine, University of Catania, Catania, Italy
Search for more papers by this author
First published: 07 February 2007
Author for correspondence: Claudio Bucolo, Department of Experimental and Clinical Pharmacology, School of Medicine, University of Catania, Viale A. Doria 6, I-95125 Catania, Italy (fax +39-095-7384238, e-mail
[email protected]).
No abstract is available for this article.
References
- 1
Kaja S,
Yang SH,
Wei J et al.
Oestrogen protects the inner retina from apoptosis and ischaemia-induced loss of Vesl-1L/Homer 1c immunoreactive synaptic connections.
Invest Ophthalmol Vis Sci
2003; 44: 3155–62.
- 2
Bucolo C,
Drago F.
Effects of neurosteroids on ischaemia-reperfusion injury in the rat retina: role of σ1 recognition sites.
Eur J Pharmacol
2004; 498: 111–4.
- 3
Bucolo C,
Drago F,
Lin LR,
Reddy VN.
Neuroactive steroids protect retinal pigment epithelium against oxidative stress.
Neuroreport
2005; 16: 1203–7.
- 4
Maurice T,
Urani A,
Phan VL,
Romieu P.
The interaction between neuroactive steroids and the σ1 receptor function: behavioural consequences and therapeutic opportunities.
Brain Res Rev
2001; 37: 116–32.
- 5
Ola MS,
Moore P,
El-Sherbeny A et al.
Expression pattern of sigma receptor 1 m RNA and protein in mammalian retina.
Brain Res Mol Brain Res
2002; 95: 86–95.
- 6
Nonaka A,
Kiryu J,
Tsujikawa A et al.
Administration of 17β-estradiol attenuates retinal ischaemia-reperfusion injury in rats.
Invest Ophthalmol Vis Sci
2000; 41: 2689–96.
- 7
Cao W,
Rajala RVS,
Li F et al.
Neuroprotective effect of oestrogen upon retinal neurons in vitro. In: V LaVail (ed.).
Retinal Degenerations: Mechanisms and Experimental Therapy.
Kluwer Academic, New York, 2003; 395–402.
- 8
Weaver CE Jr,
Park-Chung M,
Gibbs TT,
Farb DH.
17β-Estradiol protects against NMDA-induced excitotoxicity by direct inhibition of NMDA receptors.
Brain Res
1997; 761: 338–41.