Volume 87, Issue 6 pp. 680-684

Changes in Doppler ultrasonography in asphyxiated term infants with hypoxic-ischaemic encephalopathy

P Ilves

Corresponding Author

P Ilves

Departments of Paediatrics, University of Tartu, Tartu, Estonia

P Ilves, Department of Paediatrics, Children's Hospital of University of Tartu, 6 Lunini Street, EE2400 Tartu, EstoniaSearch for more papers by this author
R Talvik

R Talvik

Anaesthesiology and Intensive Care, University of Tartu, Tartu, Estonia

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T Talvik

T Talvik

Departments of Paediatrics, University of Tartu, Tartu, Estonia

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First published: 02 January 2007
Citations: 43

Abstract

Cerebral blood flow velocity was assessed by pulsed-Doppler ultrasonography in 39 asphyxiated and 35 healthy term newborn infants during the first days of life. Asphyxiated infants, investigated at the age of 12 ± 2h, with moderate stage hypoxic-ischaemic encephalopathy (HIE) (n= 7) had decreased (15.6 ± 3.9cm/s) and infants with severe stage of HIE (n= 8) increased (26.5 ± 9.6 cm/s) mean cerebral blood flow velocity in medial cerebral artery compared to the control group (20.9 ± 3.7 cm/s). Four out of six infants with severe stage of HIE and mean cerebral blood flow velocity of 3 SD above the mean for normal infants at the age of 12 h died and two developed multicystic encephalopathy during the neonatal period. We conclude that severe post-hypoxic increase of mean cerebral blood flow velocity at the age of 12 ± 2 h is connected with development of severe stage HIE and poor prognosis.

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