Adhesion inhibitory activity of β-lactoglobulin isolated from infant formulae

Corresponding Author

AC Ouwehand

Centre for Biotechnology, University of Turku, Åbo Akademi University, Turku, Finland

AC Ouwehand, Department of Biochemistry and Food Chemistry, University of Turku, FIN-20014 Turku, FinlandSearch for more papers by this author

SJ Salminen,

SJ Salminen

Department of Food Chemistry, University of Turku, Åbo Akademi University, Turku, Finland

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AC Ouwehand,

Corresponding Author

AC Ouwehand

Centre for Biotechnology, University of Turku, Åbo Akademi University, Turku, Finland

AC Ouwehand, Department of Biochemistry and Food Chemistry, University of Turku, FIN-20014 Turku, FinlandSearch for more papers by this author

SJ Salminen,

SJ Salminen

Department of Food Chemistry, University of Turku, Åbo Akademi University, Turku, Finland

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First published: 02 January 2007

https://doi.org/10.1111/j.1651-2227.1998.tb01491.x

Citations: 2

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Abstract

β-Lactoglobulin was isolated from infant formulae that were ultra high temperature (UHT) -treated, sterilized or spray-dried. The effect of the isolated β-lactoglobulin on SfaII-fimbriae-mediated adhesion of Escherichia coli to human ileostomy glycoproteins was studied in vitro.β-Lactoglobulin isolated from sterilized formulae was found to perform significantly less well than preparations from spray-dried formulae (p= 0:05). Great heterogeneity was observed in the adhesion inhibitory capacity of β-lactoglobulin isolated from UHT-treated formulae. Therefore, no significant difference was observed between UHT-treated and sterilized formulae or spray-dried formulae (p < 0:10). It can be hypothesized that β-lactoglobulin from spray-dried and some UHT-treated infant formulae may affect the colonization of mucous membranes by E. coli strains causing neonatal septicaemia and meningitis.

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Volume87, Issue5

May 1998

Pages 491-493

Adhesion inhibitory activity of β-lactoglobulin isolated from infant formulae

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Adhesion inhibitory activity of β-lactoglobulin isolated from infant formulae

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