Volume 68, Issue 1 pp. 1-7
Review Article

Changes in the maternal cytokine profile in pregnancies complicated by fetal growth restriction

Edward Mullins

Edward Mullins

Queen Charlotte's and Chelsea Hospital, Imperial College, London, UK

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Tomas Prior

Tomas Prior

Queen Charlotte's and Chelsea Hospital, Imperial College, London, UK

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Irene Roberts

Irene Roberts

Hammersmith Hospital and Imperial College, London, UK

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Sailesh Kumar

Corresponding Author

Sailesh Kumar

Queen Charlotte's and Chelsea Hospital, Imperial College, London, UK

*Correspondence

Sailesh Kumar, Centre for Fetal Care, Queen Charlotte's and Chelsea Hospital, Ducane Road, London, W12 OHS, UK

E-mail. [email protected]

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First published: 26 April 2012
Citations: 21

Abstract

Fetal growth restriction (FGR) is an important and poorly understood condition of pregnancy, which results in significant fetal, neonatal and long-term morbidity and mortality. The aetiology of FGR is unknown and is likely to result from sub-optimal placental implantation and feto-maternal immunological interaction. The diagnostic criteria for FGR vary between studies, and the condition often occurs with preeclampsia (PET). We present a review of studies of maternal cytokines in FGR and compare these with studies of Small for Gestational Age and PET pregnancies.

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