Combined therapy with Fludarabine and Cyclophosphamide in relapsed/resistant patients with B-cell chronic lymphocytic leukaemia and non-Hodgkin's lymphomas
Corresponding Author
Francesco Zaja M.D.
Division of Haematology, Department of Medical and Morphological Research, and Department of Bone Marrow Transplantation, Udine University Hospital, 33100 Udine, Italy
Division of Haematology, University Hospital, P.zza S. Maria della Misericordia, 33100 Udine, Italy Tel: 39 432 55 9662; fax: 39 432 55 9661Search for more papers by this authorAdolfo Rogato
Division of Haematology, Department of Medical and Morphological Research, and Department of Bone Marrow Transplantation, Udine University Hospital, 33100 Udine, Italy
Search for more papers by this authorDomenico Russo
Division of Haematology, Department of Medical and Morphological Research, and Department of Bone Marrow Transplantation, Udine University Hospital, 33100 Udine, Italy
Search for more papers by this authorLuciana Marin
Division of Haematology, Department of Medical and Morphological Research, and Department of Bone Marrow Transplantation, Udine University Hospital, 33100 Udine, Italy
Search for more papers by this authorFederico Silvestri
Division of Haematology, Department of Medical and Morphological Research, and Department of Bone Marrow Transplantation, Udine University Hospital, 33100 Udine, Italy
Search for more papers by this authorMichele Baccarani Chair
Division of Haematology, Department of Medical and Morphological Research, and Department of Bone Marrow Transplantation, Udine University Hospital, 33100 Udine, Italy
Search for more papers by this authorCorresponding Author
Francesco Zaja M.D.
Division of Haematology, Department of Medical and Morphological Research, and Department of Bone Marrow Transplantation, Udine University Hospital, 33100 Udine, Italy
Division of Haematology, University Hospital, P.zza S. Maria della Misericordia, 33100 Udine, Italy Tel: 39 432 55 9662; fax: 39 432 55 9661Search for more papers by this authorAdolfo Rogato
Division of Haematology, Department of Medical and Morphological Research, and Department of Bone Marrow Transplantation, Udine University Hospital, 33100 Udine, Italy
Search for more papers by this authorDomenico Russo
Division of Haematology, Department of Medical and Morphological Research, and Department of Bone Marrow Transplantation, Udine University Hospital, 33100 Udine, Italy
Search for more papers by this authorLuciana Marin
Division of Haematology, Department of Medical and Morphological Research, and Department of Bone Marrow Transplantation, Udine University Hospital, 33100 Udine, Italy
Search for more papers by this authorFederico Silvestri
Division of Haematology, Department of Medical and Morphological Research, and Department of Bone Marrow Transplantation, Udine University Hospital, 33100 Udine, Italy
Search for more papers by this authorMichele Baccarani Chair
Division of Haematology, Department of Medical and Morphological Research, and Department of Bone Marrow Transplantation, Udine University Hospital, 33100 Udine, Italy
Search for more papers by this author
References
- 1 Keating MJ, Kantarjian H, Talpaz M, et al. Fludarabine: a new agent with major activity against chronic lymphocytic leukemia. Blood 1989: 74: 19–25.
- 2 O'Brien S, Kantarjian H, Beran M, et al. Results of Fludarabine and prednisone therapy in 264 patients with chronic lymphocytic leukemia with multivariate analysis-derived prognostic model for response to treatment. Blood 1993: 82: 1695–1700.
- 3 Hochster HS, Kyungmann K, Green MD, et al. Activity of Fludarabine in previously treated non-Hodgkin's low-grade lymphoma: results of an Eastern Cooperative Oncology Group Study. J Clin Oncol 1992: 1: 28–32.
- 4 Pigatou A, Rohatiner A, Whelan JS, et al. Fludarabine in low-grade lymphoma. Semin Oncol 1993: 5: 24–27.
- 5 McLaughlin P, Hagemeister FB, Swan F, et al. Phase I study of the combination of Fludarabine, mitoxantrone and dexamethasone in low-grade lymphoma. J Clin Oncol 1994: 12: 575–579.
- 6 Keating MJ, O'Brien S, McLaughlin P, Kantarjian H, Cabanillas F. Fludarabine (Flu) combinations in the management of chronic lymphocytic leukemia (CLL) and low grade lymphoma (LGL). Ann Oncol 1996: 7 (Suppl 3): 110a.
- 7
Cheson BD,
Bennet JM,
Grever M, et al.
National Cancer Institute-sponsored Working Group guidelines for Chronic Lymphocytic Leukemia: revised guidelines for diagnosis and treatment.
Blood
1996: 12: 4990–4997.
10.1182/blood.V87.12.4990.bloodjournal87124990 Google Scholar
Citing Literature
