Absence of antibodies to HTLV-1 in sera from Hungarian MS patients
Corresponding Author
F. Koike
Division of Demyelinating Disease and Aging, National Institute of Neuroscience, Tokyo 187, Japan
Division of Demyelinating Disease and Aging National Institute of Neuroscience, NCNP 4–1–1 Ogawa-higashi Kodaira Tokyo 187 JapanSearch for more papers by this authorG. Pálffy
Department of Neurology and Psychiatry, University of Pécs Medical School, Hungary
Search for more papers by this authorT. Kunishita
Division of Demyelinating Disease and Aging, National Institute of Neuroscience, Tokyo 187, Japan
Search for more papers by this authorM. Yoshida
Department of Viral Oncology, Cancer Institute, Tokyo 187, Japan
Search for more papers by this authorT. Tabira
Division of Demyelinating Disease and Aging, National Institute of Neuroscience, Tokyo 187, Japan
Search for more papers by this authorCorresponding Author
F. Koike
Division of Demyelinating Disease and Aging, National Institute of Neuroscience, Tokyo 187, Japan
Division of Demyelinating Disease and Aging National Institute of Neuroscience, NCNP 4–1–1 Ogawa-higashi Kodaira Tokyo 187 JapanSearch for more papers by this authorG. Pálffy
Department of Neurology and Psychiatry, University of Pécs Medical School, Hungary
Search for more papers by this authorT. Kunishita
Division of Demyelinating Disease and Aging, National Institute of Neuroscience, Tokyo 187, Japan
Search for more papers by this authorM. Yoshida
Department of Viral Oncology, Cancer Institute, Tokyo 187, Japan
Search for more papers by this authorT. Tabira
Division of Demyelinating Disease and Aging, National Institute of Neuroscience, Tokyo 187, Japan
Search for more papers by this authorAbstract
ABSTRACT- The aim of this study is to examine the association between multiple sclerosis (MS) and anti-human T-lymphotropic virus type I (HTLV-I) antibody. Serum samples from 16 Hungarian Caucasians with MS, 2 gipsy patients with MS, 13 Hungarian Caucasians with other neurological diseases (OND) and 2 gipsy patients with OND were tested by Western blot combined with autoradiography using disrupted virus from MT-2 cell line and recombinant p24 as antigens. Negative results were obtained in all samples except for 3 Hungarian OND which were reactive to disrupted virus, but not to recombinant p24.
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