Amyotrophic choreo-acanthocytosis: a new observation in southern Europe
Corresponding Author
S. Serra
Institute of Neurological and Neurosurgical Sciences, University of Messina
Salvatore Serra, M.D. Institute of Neurological and Neurosurgical Sciences Clinica Neurologica I Policlinico Universitario 98100 Messina, ItalySearch for more papers by this authorA. Xerra
Institute of Neurological and Neurosurgical Sciences, University of Messina
Search for more papers by this authorA. Arena
Division of Neurology, Piemonte Hospital, Messina, Italy
Search for more papers by this authorCorresponding Author
S. Serra
Institute of Neurological and Neurosurgical Sciences, University of Messina
Salvatore Serra, M.D. Institute of Neurological and Neurosurgical Sciences Clinica Neurologica I Policlinico Universitario 98100 Messina, ItalySearch for more papers by this authorA. Xerra
Institute of Neurological and Neurosurgical Sciences, University of Messina
Search for more papers by this authorA. Arena
Division of Neurology, Piemonte Hospital, Messina, Italy
Search for more papers by this authorAbstract
ABSTRACT Amyotrophic choreo-acanthocytosis is a rare disease of adult onset characterized by dyskinesias, neurogenic muscular atrophy, erythrocytary acanthocytosis with normal serum lipoproteins and elevated levels of serum CPK. Presumably, this disorder is an autosomal recessively inherited trait. This disease has been described in Japanese, English, Finnish and Puertorican people. This is the first observation in the southern countries of Europe, in two members of a Calabrian family. The authors point out that amyotrophic features can occur several years before the appearance of the extrapyramidal disorders.
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