Bacterial cleavage of nitrogen to sulfone bonds in sulfamide and 1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide: formation of 2-nitrobenzamide by Gordonia sp.
Ulrike Rein,
Alasdair M. Cook,
Ulrike Rein
Department of Biology, University of Konstanz, D-78457 Konstanz, Germany
Search for more papers by this authorCorresponding Author
Alasdair M. Cook
Department of Biology, University of Konstanz, D-78457 Konstanz, Germany
*Corresponding author. Tel.: +49 (7531) 884247; Fax: +49 (7531) 882966; E-mail: [email protected]Search for more papers by this authorUlrike Rein,
Alasdair M. Cook,
Ulrike Rein
Department of Biology, University of Konstanz, D-78457 Konstanz, Germany
Search for more papers by this authorCorresponding Author
Alasdair M. Cook
Department of Biology, University of Konstanz, D-78457 Konstanz, Germany
*Corresponding author. Tel.: +49 (7531) 884247; Fax: +49 (7531) 882966; E-mail: [email protected]Search for more papers by this authorAbstract
Pure cultures of aerobic bacteria were isolated which could utilize sulfamate, sulfamide or 1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide (BTDD) as sole source of sulfur for growth and thus cleave a N–S(O)x bond. The molar growth yields indicated that each source of sulfur was utilized quantitatively. This was confirmed directly for Gordonia sp. strain BT2 utilizing BTDD, which was converted quantitatively via an unidentified intermediate to 2-nitrobenzamide. Another isolate, strain BT1, could utilize saccharin to yield salicylamide, thus cleaving both the N–S(O)x and C–S(O)x bonds.
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