Volume 25, Issue 6 pp. 662-664
Case Reports

Myasthenia Gravis—An Unexpected Cause of Respiratory Failure and Reversible Left Ventricular Dysfunction after Cardiac Surgery

Jared L. Antevil M.D.

Jared L. Antevil M.D.

Department of Cardiothoracic Surgery

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Craig G. Carroll D.O.

Craig G. Carroll D.O.

Departments of Neurology

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Peter F. Roberts M.D.

Peter F. Roberts M.D.

Department of Cardiothoracic Surgery

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Michael G. Johnston M.D.

Michael G. Johnston M.D.

Department of General Surgery, Naval Medical Center Portsmouth, Portsmouth, Virginia

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Robert G. Strange M.D.

Robert G. Strange M.D.

Department of Cardiothoracic Surgery

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First published: 27 August 2010
Citations: 4
Address for correspondence: Jared L. Antevil, M.D., C.D.R., M.C., U.S.N., Department of Cardiothoracic Surgery, Naval Medical Center Portsmouth, 620 John Paul Jones Circle, Portsmouth, VA 23708. Fax: (757)-953-2418; e-mail: [email protected]

Conflict of interest: There are no conflict of interest.

Abstract

Abstract We report a case of postpericardiotomy myasthenia gravis. A 68-year-old male patient without prior history of neuromuscular or autoimmune disorders presented with respiratory failure and severe left ventricular dysfunction four weeks after mitral valve replacement. Markedly elevated acetylcholine receptor antibodies were noted, and the patient responded promptly to immunologic therapy. Awareness of this rare but potentially fatal consequence of cardiac surgery may allow the early institution of specific treatment. (J Card Surg 2010;25:662-664)

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