Managing and understanding epilepsy in tuberous sclerosis complex
Elizabeth A. Thiele,
Elizabeth A. Thiele
Carol and James Herscot Center for TSC, Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, U.S.A.
Search for more papers by this authorElizabeth A. Thiele,
Elizabeth A. Thiele
Carol and James Herscot Center for TSC, Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, U.S.A.
Search for more papers by this authorAddress correspondence to Elizabeth A. Thiele, MD PhD, Director, Carol and James Herscot Center for TSC, Department of Neurology, Massachusetts General Hospital, Boston, MA, U.S.A. E-mail: [email protected]
No abstract is available for this article.
References
- Chu-Shore CJ, Major P, Montenegro M, Thiele E. (2009) Cyst-like tubers are associated with TSC2 and epilepsy in tuberous sclerosis complex. Neurology 72: 1165–1169.
- Crino PB, Nathanson KL, Henske EP. (2006) The tuberous sclerosis complex. N Engl J Med 355: 1345–1356.
- Dabora SL, Jozwiak S, Franz DN, Roberts PS, Nieto A, Chung J, Choy YS, Reeve MP, Thiele E, Egelhoff JC, Kasprzyk-Obara J, Domanska-Pakiela D, Kwiatkowski DJ. (2001) Mutational analysis in a cohort of 224 tuberous sclerosis patients indicates increased severity of TSC2, compared with TSC1, disease in multiple organs. Am J Hum Genet 68: 64–80.
- Jansen FE, Huffelen ACV, Rijen PCV, Leijten FSS, Jennekens-Schinkel A, Gosselaar P, Nieuwenhuizen OV, Programme DCES. (2007) Epilepsy surgery in tuberous sclerosis: the Dutch experience. Seizure 16: 445–453.
- Jarrar RG, Buchhalter JR, Raffel C. (2004) Long-term outcome of epilepsy surgery in patients with tuberous sclerosis. Neurology 62: 479–481.
- Kossoff EH, Thiele EA, Pfeifer HH, McGrogan JR, Freeman JM. (2005) Tuberous sclerosis complex and the ketogenic diet. Epilepsia 46: 1684–1686.
- Lyczkowski DA, Conant KD, Pulsifer MB, Jarrett DY, Grant PE, Kwiatkowski DJ, Thiele EA. (2007) Intrafamilial phenotypic variability in tuberous sclerosis complex. J Child Neurol 22: 1348–1355.
- Mackay MT, Weiss SK, Adams-Webber T, Ashwal S, Stephens D, Ballaban-Gill K, Baram TZ, Duchowny M, Hirtz D, Pellock JM, Shields WD, Shinnar S, Wyllie E, Snead OC 3rd. (2004) Practice parameter: medical treatment of infantile spasms: report of the American Academy of Neurology and the Child Neurology Society. Neurology 62: 1668–1681.
- Major P, Greenberg E, Khan A, Thiele EA. (2008) Pyridoxine supplementation for the treatment of levetiracetam-induced behavior side effects in children: preliminary results. Epilepsy Behav 13: 557–559.
- Major P, Rakowski S, Simon MV, Cheng ML, Eskandar E, Baron J, Leeman BA, Frosch MP, Thiele EA. (2009) Are cortical tubers epileptogenic? Evidence from electrocorticography. Epilepsia 50: 147–154.
- Muzykewicz DA, Costello DJ, Halpern EF, Thiele EA. (2009) Infantile spasms in tuberous sclerosis complex: prognostic utility of EEG. Epilepsia 50: 290–296.
- O’Callaghan FJK, Harris T, Joinson C, Bolton P, Noakes M, Presdee D, Renowden S, Shiell A, Martyn CN, Osborne JP. (2004) The relation of infantile spasms, tubers, and intelligence in tuberous sclerosis complex. Arch Dis Child 89: 530–533.
- Parain D, Penniello MJ, Berquen P, Delangre T, Billard C, Murphy JV. (2001) Vagal nerve stimulation in tuberous sclerosis complex patients. Pediatr Neurol 25: 213–216.
- Staley BA, Montenegro MA, Major P, Muzykewicz DA, Halpern EF, Kopp CMC, Newberry P, Thiele EA. (2008) Self-injurious behavior and tuberous sclerosis complex: frequency and possible associations in a population of 257 patients. Epilepsy Behav 13: 650–653.
- Tavazoie SF, Alvarez VA, Ridenour DA, Kwiatkowski DJ, Sabatini BL. (2005) Regulation of neuronal morphology and function by the tumor suppressors Tsc1 and Tsc2. Nat Neurosci 8: 1727–1734.
- Weiner HL, Carlson C, Ridgway EB, Zaroff CM, Miles D, LaJoie J, Devinsky O. (2006) Epilepsy surgery in young children with tuberous sclerosis: results of a novel approach. Pediatrics 117: 1494–1502.
- Winterkorn EB, Pulsifer MB, Thiele EA. (2007) Cognitive prognosis of patients with tuberous sclerosis complex. Neurology 68: 62–64.
- Zeng L-H, Xu L, Gutmann DH, Wong M. (2008) Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex. Ann Neurol 63: 444–453.
