Development and In Vitro Characterization of a New Artificial Flow Channel
Corresponding Author
Daniel Wendt
Department of Thoracic and Cardiovascular Surgery, West-German Heart Center Essen, University Hospital Essen
Dr. Daniel Wendt, Department of Thoracic and Cardiovascular Surgery, West-German Heart Center Essen, University Hospital Essen, Hufelandstraße 55, 45122 Essen, Germany. E-mail: [email protected]Search for more papers by this authorSebastian Stühle
Department of Thoracic and Cardiovascular Surgery, West-German Heart Center Essen, University Hospital Essen
University of Duisburg-Essen, Essen, Germany
Search for more papers by this authorMatthias Thielmann
Department of Thoracic and Cardiovascular Surgery, West-German Heart Center Essen, University Hospital Essen
Search for more papers by this authorKonstantinos Tsagakis
Department of Thoracic and Cardiovascular Surgery, West-German Heart Center Essen, University Hospital Essen
Search for more papers by this authorHermann Wendt
Department of Thoracic and Cardiovascular Surgery, West-German Heart Center Essen, University Hospital Essen
Search for more papers by this authorHeinz Jakob
Department of Thoracic and Cardiovascular Surgery, West-German Heart Center Essen, University Hospital Essen
Search for more papers by this authorWojciech Kowalczyk
University of Duisburg-Essen, Essen, Germany
Search for more papers by this authorCorresponding Author
Daniel Wendt
Department of Thoracic and Cardiovascular Surgery, West-German Heart Center Essen, University Hospital Essen
Dr. Daniel Wendt, Department of Thoracic and Cardiovascular Surgery, West-German Heart Center Essen, University Hospital Essen, Hufelandstraße 55, 45122 Essen, Germany. E-mail: [email protected]Search for more papers by this authorSebastian Stühle
Department of Thoracic and Cardiovascular Surgery, West-German Heart Center Essen, University Hospital Essen
University of Duisburg-Essen, Essen, Germany
Search for more papers by this authorMatthias Thielmann
Department of Thoracic and Cardiovascular Surgery, West-German Heart Center Essen, University Hospital Essen
Search for more papers by this authorKonstantinos Tsagakis
Department of Thoracic and Cardiovascular Surgery, West-German Heart Center Essen, University Hospital Essen
Search for more papers by this authorHermann Wendt
Department of Thoracic and Cardiovascular Surgery, West-German Heart Center Essen, University Hospital Essen
Search for more papers by this authorHeinz Jakob
Department of Thoracic and Cardiovascular Surgery, West-German Heart Center Essen, University Hospital Essen
Search for more papers by this authorWojciech Kowalczyk
University of Duisburg-Essen, Essen, Germany
Search for more papers by this authorAbstract
To date, cardiac valve diseases are considered as a major public health problem and most frequently, the aortic valve is affected. To treat high-risk patients, catheter-based techniques have been developed recently, avoiding open heart surgery and/or cardiopulmonary bypass. Although these sophisticated and rapidly emerging catheter-based technologies do allow a minimally invasive treatment option of high-risk patients on the one hand, further developments and in vitro testing under physiological conditions are necessary, on the other hand, in order to further optimize them for clinical routines. Therefore, we present the concept of a new multifunctional flow channel, offering (i) the possibility of transapical access; (ii) the simulation of physiological flow conditions; and (iii) the evaluation of the fluid flow by 2D particle image velocimetry within a wide range of parameters.
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