Volume 31, Issue 5 pp. 405-408

Cleveland Clinic PediPump Lamb Cadaver Fitting Studies

Faruk Cingoz,

Faruk Cingoz

Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic; and

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Kiyotaka Fukamachi,

Corresponding Author

Kiyotaka Fukamachi

Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic; and

Dr. Kiyotaka Fukamachi, Department of Biomedical Engineering/ND20, 9500 Euclid Avenue, Cleveland, OH 44195, USA. E-mail: [email protected]Search for more papers by this author

Yoshio Ootaki,

Yoshio Ootaki

Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic; and

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Keiji Kamohara,

Keiji Kamohara

Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic; and

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Masatoshi Akiyama,

Masatoshi Akiyama

Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic; and

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Chiyo Ootaki,

Chiyo Ootaki

Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic; and

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Michael W. Kopcak,

Michael W. Kopcak

Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic; and

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Jenny Liu,

Jenny Liu

Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic; and

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Angela Noecker,

Angela Noecker

Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic; and

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Dave Dudzinski,

Dave Dudzinski

Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic; and

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William A. Smith,

William A. Smith

Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic; and

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Brian W. Duncan,

Brian W. Duncan

Department of Pediatric and Congenital Heart Surgery, Children's Hospital, Cleveland Clinic, Cleveland, OH, USA

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Faruk Cingoz,

Faruk Cingoz

Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic; and

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Kiyotaka Fukamachi,

Corresponding Author

Kiyotaka Fukamachi

Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic; and

Dr. Kiyotaka Fukamachi, Department of Biomedical Engineering/ND20, 9500 Euclid Avenue, Cleveland, OH 44195, USA. E-mail: [email protected]Search for more papers by this author

Yoshio Ootaki,

Yoshio Ootaki

Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic; and

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Keiji Kamohara,

Keiji Kamohara

Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic; and

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Masatoshi Akiyama,

Masatoshi Akiyama

Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic; and

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Chiyo Ootaki,

Chiyo Ootaki

Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic; and

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Michael W. Kopcak,

Michael W. Kopcak

Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic; and

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Jenny Liu,

Jenny Liu

Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic; and

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Angela Noecker,

Angela Noecker

Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic; and

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Dave Dudzinski,

Dave Dudzinski

Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic; and

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William A. Smith,

William A. Smith

Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic; and

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Brian W. Duncan,

Brian W. Duncan

Department of Pediatric and Congenital Heart Surgery, Children's Hospital, Cleveland Clinic, Cleveland, OH, USA

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First published: 26 April 2007

https://doi.org/10.1111/j.1525-1594.2007.00400.x

Citations: 6

Presented in part at the 14th Congress of the International Society for Rotary Blood Pumps held August 31–September 2, 2006, in Leuven, Belgium.

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Abstract

Abstract: We are developing the PediPump, a magnetically suspended, mixed-flow pump, as an implantable pediatric ventricular assist device (VAD). Lamb cadaver fitting studies were performed to determine the optimal pump location and optimal design of the inflow and outflow conduits for chronic in vivo studies. A prototype of the PediPump right and left ventricular assist devices (RVAD and LVAD, respectively) were implanted via a sternotomy or left thoracotomy in four lamb cadavers (3.7–34.2 kg). Via a sternotomy, the RVAD and LVAD required long inflow cannulas when placed into the right or left thoracic cavities, respectively. Via a left thoracotomy, with both pumps implanted in the left thoracic cavity, the RVAD required a 70° inflow cannula and a bent outflow graft while the LVAD required a 130° inflow cannula and a straight outflow graft. In conclusion, left thoracotomy provided optimal fitting for both LVAD and RVAD for the small lamb model.

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Volume31, Issue5

May 2007

Pages 405-408

Cleveland Clinic PediPump Lamb Cadaver Fitting Studies

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