A Case of S-100-Positive Juvenile Xanthogranuloma: A Longitudinal Observation
Address correspondence to Yosuke Yamamoto, M.D., Department of Epidemiology and Healthcare Research, Graduate School of Medicine, Kyoto University, Yoshida Konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan, or e-mail: [email protected].
Abstract
Abstract: We present the case of a 9-month-old boy with yellow-brown papules that gradually increased in number over a period of 6 months without systemic involvement. Our case was clinicopathologically diagnosed as S-100-positive juvenile xanthogranuloma, and longitudinal observation revealed that strong S-100 reactivity disappeared in parallel with maturation of the lesions within 2 years after the initial diagnosis. These findings add to the complexity in cells of origin of this disorder.
