Endemic Pemphigus Foliaceus in Venezuela: Report of Two Children

Francisco González M.D.

Department of Dermatology, Hospital Universitario de Caracas, “Luis Razetti” School of Medicine, Central University of Venezuela, Caracas, Venezuela

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Ana Maria Sáenz M.D.,

Ana Maria Sáenz M.D.

Department of Dermatology, Hospital Universitario de Caracas, “Luis Razetti” School of Medicine, Central University of Venezuela, Caracas, Venezuela

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Antonietta Cirocco M.D.,

Antonietta Cirocco M.D.

Department of Dermatology, Hospital Universitario de Caracas, “Luis Razetti” School of Medicine, Central University of Venezuela, Caracas, Venezuela

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Inés Maria Tacaronte M.D.,

Inés Maria Tacaronte M.D.

Department of Dermatology, Hospital Universitario de Caracas, “Luis Razetti” School of Medicine, Central University of Venezuela, Caracas, Venezuela

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Javier Enrique Fajardo M.D.,

Javier Enrique Fajardo M.D.

Department of Dermatology, Hospital Universitario de Caracas, “Luis Razetti” School of Medicine, Central University of Venezuela, Caracas, Venezuela

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Adriana Calebotta M.D.,

Adriana Calebotta M.D.

Department of Dermatology, Hospital Universitario de Caracas, “Luis Razetti” School of Medicine, Central University of Venezuela, Caracas, Venezuela

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Francisco González M.D.,

Francisco González M.D.

Department of Dermatology, Hospital Universitario de Caracas, “Luis Razetti” School of Medicine, Central University of Venezuela, Caracas, Venezuela

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Ana Maria Sáenz M.D.,

Ana Maria Sáenz M.D.

Department of Dermatology, Hospital Universitario de Caracas, “Luis Razetti” School of Medicine, Central University of Venezuela, Caracas, Venezuela

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Antonietta Cirocco M.D.,

Antonietta Cirocco M.D.

Department of Dermatology, Hospital Universitario de Caracas, “Luis Razetti” School of Medicine, Central University of Venezuela, Caracas, Venezuela

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Inés Maria Tacaronte M.D.,

Inés Maria Tacaronte M.D.

Department of Dermatology, Hospital Universitario de Caracas, “Luis Razetti” School of Medicine, Central University of Venezuela, Caracas, Venezuela

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Javier Enrique Fajardo M.D.,

Javier Enrique Fajardo M.D.

Department of Dermatology, Hospital Universitario de Caracas, “Luis Razetti” School of Medicine, Central University of Venezuela, Caracas, Venezuela

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Adriana Calebotta M.D.,

Adriana Calebotta M.D.

Department of Dermatology, Hospital Universitario de Caracas, “Luis Razetti” School of Medicine, Central University of Venezuela, Caracas, Venezuela

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First published: 04 April 2006

https://doi.org/10.1111/j.1525-1470.2006.00197.x

Citations: 11

Address correspondence to Ana Maria Sáenz, M.D., CCS 6140, 4440 NW 73rd Ave., Miami, Florida 33166, or e-mail: [email protected].

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Abstract

Abstract: Two native Yanomami children from the Venezuelan Amazonia with erythroderma were hospitalized on our service. Clinical, histologic, and immunofluorescence studies diagnosed endemic pemphigus foliaceous. Human leukocyte antigen class II showed DRB1*04 subtype *0411, which has not been previously associated with this disease. However, it shares a common epitope with all the human leukocyte antigen DRB1 alleles that have been involved in this disease among Brazilian populations. Although this condition is endemic in Brazil, our patients are the first two reported in Venezuela.

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Volume23, Issue2

March 2006

Pages 132-135

Endemic Pemphigus Foliaceus in Venezuela: Report of Two Children

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Endemic Pemphigus Foliaceus in Venezuela: Report of Two Children

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