Regional localization of polymorphic markers on chromosome 10 by physical and genetic mapping
C. G. P. MATHEW
Cancer Research Campaign Human Cancer Genetics Research Group, Institute of Cancer Research, Surrey/Department of Pathology, University of Cambridge, UK
Search for more papers by this authorW. WAKELING
Cancer Research Campaign Human Cancer Genetics Research Group, Institute of Cancer Research, Surrey/Department of Pathology, University of Cambridge, UK
Search for more papers by this authorE. JONES
Cancer Research Campaign Human Cancer Genetics Research Group, Institute of Cancer Research, Surrey/Department of Pathology, University of Cambridge, UK
Search for more papers by this authorD. EASTON
Section of Epidemiology, Institute of Cancer Research, Surrey, UK
Search for more papers by this authorR. FISHER
Cancer Research Campaign Human Cancer Genetics Research Group, Institute of Cancer Research, Surrey/Department of Pathology, University of Cambridge, UK
Search for more papers by this authorC. STRONG
Cancer Research Campaign Human Cancer Genetics Research Group, Institute of Cancer Research, Surrey/Department of Pathology, University of Cambridge, UK
Search for more papers by this authorB. SMITH
Cancer Research Campaign Human Cancer Genetics Research Group, Institute of Cancer Research, Surrey/Department of Pathology, University of Cambridge, UK
Search for more papers by this authorK. CHIN
Cancer Research Campaign Human Cancer Genetics Research Group, Institute of Cancer Research, Surrey/Department of Pathology, University of Cambridge, UK
Search for more papers by this authorP. LITTLE
Department of Biochemistry, Imperial College of Science and Technology, London, UK
Search for more papers by this authorY. NAKAMURA
Howard Hughes Medical Institute, University of Utah, Salt Lake City, Utah, USA
Search for more papers by this authorT. B. SHOWS
Roswell Park Memorial Institute, Buffalo, New York, USA
Search for more papers by this authorP. J. GOODFELLOW
Department of Medical Genetics, University of British Columbia, Vancouver, Canada
Search for more papers by this authorS. POVEY
MRC Human Biochemical Genetics Unit, The, Galton Laboratory, University College London, UK
Search for more papers by this authorB. A. J. PONDER
Cancer Research Campaign Human Cancer Genetics Research Group, Institute of Cancer Research, Surrey/Department of Pathology, University of Cambridge, UK
Search for more papers by this authorC. G. P. MATHEW
Cancer Research Campaign Human Cancer Genetics Research Group, Institute of Cancer Research, Surrey/Department of Pathology, University of Cambridge, UK
Search for more papers by this authorW. WAKELING
Cancer Research Campaign Human Cancer Genetics Research Group, Institute of Cancer Research, Surrey/Department of Pathology, University of Cambridge, UK
Search for more papers by this authorE. JONES
Cancer Research Campaign Human Cancer Genetics Research Group, Institute of Cancer Research, Surrey/Department of Pathology, University of Cambridge, UK
Search for more papers by this authorD. EASTON
Section of Epidemiology, Institute of Cancer Research, Surrey, UK
Search for more papers by this authorR. FISHER
Cancer Research Campaign Human Cancer Genetics Research Group, Institute of Cancer Research, Surrey/Department of Pathology, University of Cambridge, UK
Search for more papers by this authorC. STRONG
Cancer Research Campaign Human Cancer Genetics Research Group, Institute of Cancer Research, Surrey/Department of Pathology, University of Cambridge, UK
Search for more papers by this authorB. SMITH
Cancer Research Campaign Human Cancer Genetics Research Group, Institute of Cancer Research, Surrey/Department of Pathology, University of Cambridge, UK
Search for more papers by this authorK. CHIN
Cancer Research Campaign Human Cancer Genetics Research Group, Institute of Cancer Research, Surrey/Department of Pathology, University of Cambridge, UK
Search for more papers by this authorP. LITTLE
Department of Biochemistry, Imperial College of Science and Technology, London, UK
Search for more papers by this authorY. NAKAMURA
Howard Hughes Medical Institute, University of Utah, Salt Lake City, Utah, USA
Search for more papers by this authorT. B. SHOWS
Roswell Park Memorial Institute, Buffalo, New York, USA
Search for more papers by this authorP. J. GOODFELLOW
Department of Medical Genetics, University of British Columbia, Vancouver, Canada
Search for more papers by this authorS. POVEY
MRC Human Biochemical Genetics Unit, The, Galton Laboratory, University College London, UK
Search for more papers by this authorB. A. J. PONDER
Cancer Research Campaign Human Cancer Genetics Research Group, Institute of Cancer Research, Surrey/Department of Pathology, University of Cambridge, UK
Search for more papers by this authorSUMMARY
The human vimentin gene and a random DNA segment (D10S39) were mapped to the short arm of human chromosome 10 by linkage analysis. A panel of somatic cell hybrids and monosomy cell-lines, which divide chromosome 10 into seven regions, was used to localize 10 polymorphic markers on this chromosome. The physical map locations obtained correlate well with linkage maps of chromosome 10. Two markers which have been shown to be closely linked to the gene for multiple endocrine neoplasia type 2A map distal to a translocation breakpoint in band 10qll.2
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