The prognostic value of the acute-phase response in stroke recurrence
Corresponding Author
A. Chamorro
Neurology Service, Hospital Clinic i Provincial, Villaroel 170, 08036 Barcelona, Spain
Neurology Service, Hospital Clinic i Provincial, Villaroel 170, 08036 Barcelona, SpainSearch for more papers by this authorN. Vila
Neurology Service, Hospital Clinic i Provincial, Villaroel 170, 08036 Barcelona, Spain
Search for more papers by this authorR. Blanc
Neurology Service, Hospital Clinic i Provincial, Villaroel 170, 08036 Barcelona, Spain
Search for more papers by this authorA. Saiz
Neurology Service, Hospital Clinic i Provincial, Villaroel 170, 08036 Barcelona, Spain
Search for more papers by this authorC. Ascaso
Epidemiology and Biostatistics Service of the Department of Medicine, Hospital Clinic i Provincial, Villaroel 170, 08036 Barcelona, Spain
Search for more papers by this authorR. Deulofeu
Department of Clinical Biochemistry, Hospital Clinic i Provincial, Villaroel 170, 08036 Barcelona, Spain
Search for more papers by this authorCorresponding Author
A. Chamorro
Neurology Service, Hospital Clinic i Provincial, Villaroel 170, 08036 Barcelona, Spain
Neurology Service, Hospital Clinic i Provincial, Villaroel 170, 08036 Barcelona, SpainSearch for more papers by this authorN. Vila
Neurology Service, Hospital Clinic i Provincial, Villaroel 170, 08036 Barcelona, Spain
Search for more papers by this authorR. Blanc
Neurology Service, Hospital Clinic i Provincial, Villaroel 170, 08036 Barcelona, Spain
Search for more papers by this authorA. Saiz
Neurology Service, Hospital Clinic i Provincial, Villaroel 170, 08036 Barcelona, Spain
Search for more papers by this authorC. Ascaso
Epidemiology and Biostatistics Service of the Department of Medicine, Hospital Clinic i Provincial, Villaroel 170, 08036 Barcelona, Spain
Search for more papers by this authorR. Deulofeu
Department of Clinical Biochemistry, Hospital Clinic i Provincial, Villaroel 170, 08036 Barcelona, Spain
Search for more papers by this authorAbstract
We measured the erythrocyte sedimentation rate (ESR) in 318 acute stroke patients receiving heparin to evaluate its predictor value on the risk of early recurrence (first two weeks). The cumulative risks of early recurrence were 2.93 ± 1.85% for the low ESR group, and 9.77 ± 3.25% for the high ESR group. With logistic regression the risk of early stroke recurrence was associated to the ESR group (OR 3.55, 95% IC 1.24-10.15), and a history of recent (< 1 week) (OR 6.95, 95% IC 2.06–23.42), or remote TIA (OR 4.27, 95% IC 1.22-14.91). These results pointed to an inflammatory component in the pathogenesis of early recurrent stroke.
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