Volume 16, Issue 5 pp. 568-572

Transient loss of motor-evoked responses associated with caudal injection of morphine in a patient with spondylolisthesis undergoing spinal fusion

PETER R.J. GIBSON MBBS FANZCA

PETER R.J. GIBSON MBBS FANZCA

Children's Hospital at Westmead, Westmead, Australia

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SARAH JOHNSTON FCA(SA) MBCHB

SARAH JOHNSTON FCA(SA) MBCHB

Children's Hospital at Westmead, Westmead, Australia

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JIM LAGOPOULOS BSC MBIOMEDE PHD FAINM

JIM LAGOPOULOS BSC MBIOMEDE PHD FAINM

Department of Neurophysiology, School of Psychiatry, University of NSW, Westmead Hospital, Westmead, Australia

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JOHN L. CUMMINE MBBS FRACS

JOHN L. CUMMINE MBBS FRACS

Children's Hospital at Westmead, Westmead, Australia

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First published: 29 November 2005
Citations: 6
Peter R.J. Gibson, Staff Specialist Anaesthetist, Children's Hospital at Westmead, Westmead, NSW 2145, Australia (email: [email protected]).

Summary

A 7-year-old girl having posterior spinal fusion for Grade 3 anterior spondylolisthesis at the L5/S1 level was administered 2.5 mg of morphine in 10 ml saline via the caudal epidural route before surgery. Motor-evoked responses were markedly diminished in her lower limbs for 1 h following this but returned spontaneously. She suffered no neurological injury. The cause for this is postulated to be transient cauda equina compression from the volume of injectate. This complication of caudal injection has not been reported before. The possible mechanisms for this are discussed. We believe that significant L5/S1 spondylolisthesis should be considered a contraindication to the use of caudal epidural injections.

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