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Liposome-Entrapped GABA Modifies Kindling-Induced Seizures in Rats
Norio Mori M.D.,
Kenji Terayama M.D.,
Takashi Sato M.D.,
Hisashi Kumashiro M.D.,
Corresponding Author
Norio Mori M.D.
Department of Neuropsychiatry, Fukushima Medical School, Fukushima
Department of Neuropsychiatry, Fukushima Medical School, 4–45 Sugitsuma-cho, Fukushima-shi, Fukushima 960, Japan.Search for more papers by this authorKenji Terayama M.D.
Department of Neuropsychiatry, Fukushima Medical School, Fukushima
Search for more papers by this authorTakashi Sato M.D.
Department of Neuropsychiatry, Fukushima Medical School, Fukushima
Search for more papers by this authorHisashi Kumashiro M.D.
Department of Neuropsychiatry, Fukushima Medical School, Fukushima
Search for more papers by this authorNorio Mori M.D.,
Kenji Terayama M.D.,
Takashi Sato M.D.,
Hisashi Kumashiro M.D.,
Corresponding Author
Norio Mori M.D.
Department of Neuropsychiatry, Fukushima Medical School, Fukushima
Department of Neuropsychiatry, Fukushima Medical School, 4–45 Sugitsuma-cho, Fukushima-shi, Fukushima 960, Japan.Search for more papers by this authorKenji Terayama M.D.
Department of Neuropsychiatry, Fukushima Medical School, Fukushima
Search for more papers by this authorTakashi Sato M.D.
Department of Neuropsychiatry, Fukushima Medical School, Fukushima
Search for more papers by this authorHisashi Kumashiro M.D.
Department of Neuropsychiatry, Fukushima Medical School, Fukushima
Search for more papers by this authorNo abstract is available for this article.
REFERENCE
- 1 Biswas, B. and Carlsson, A.: The effect of intracerebroventricular administered GABA on brain monoamine metabolism. Naunyn Schmiedeberg's Arch Pharmacol 299: 41–46, 1977.
- 2 Engel, J. and Katzman, R.: Facilitation of amygdaloid kindling by lesions of the stria terminalis. Brain Res 122: 137–142, 1977.
- 3 Goddard, G.V., McIntyre, D.C. and Leech, C.K.: A permanent change in brain function resulting from daily electrical stimulation. Exp Neurol 25: 295–330, 1969.
- 4 Gregoriadis, G.: The carrier potential of liposomes in biology and medicine. New Engl J Med 295: 704–710, 1976.
- 5 Hespe, W., Roberts, E. and Prins, H.: Autoradiographic investigation of the distribution of [14GABA in tissues of normal and aminooxyacetic acid-treated mice. Brain Res 14: 663–671, 1969.
- 6
Le Gal La Salle G.: Inhibition of kindling-induced generalized seizures by aminooxyacetic acid.
Can J Physiol Pharmacol
58: 7–11, 1979.
10.1139/y80-002 Google Scholar
- 7 Maynert, E.W., Marczynski, T.J. and Browning, R.A.: The role of the neuro-transmitters in the epilepsies. In: W. J. Fried-lander (ed.), Advances in neurology. Raven Press, New York , pp. 79–147, 1975.
- 8 McIntyre, D.C.: Catecholamine involvement in amygdala kindling in the rat. In: J. A. Wada (ed.), Kindling 2. Raven Press, New York , pp. 67–85, 1981.
- 9 Myslobodsky, M.S. and Valenstein, E.S.: Amygdaloid kindling and the GABA system, Epilepsia 21: 163–175, 1980.
- 10 Racine, R.J.: Modification of seizure activity by electrical stimulation. II. Motor seizure. Electroencephalogr Clin Neuro-physiol 32: 281–294, 1972.