HLA phenotypes of 64 Italian pediatric patients with celiac disease (CD) were compared with those of a group of healthy controls. DR3 and DR7 are significantly increased as reported in other populations. In addition an increase of heterozygotes DR5/DR7 was observed in our patients. The Hardy-Weinberg distribution in the patients group shows a disequilibrium due to the genotype DR5/DR7. Our data confirm that more than one HLA gene product is associated with CD: one with DR3 and the other with DR7.

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Volume46, Issue2

February 1984

Pages 102-106

HLA-ABC and DR Antigens in Celiac Disease

A Study in a Pediatric Italian Population¹

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HLA-ABC and DR Antigens in Celiac Disease

A Study in a Pediatric Italian Population1

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A Study in a Pediatric Italian Population¹