Synthesis of α-thiophenylglycine peptides
Novel peptide substrates useful in the study of microbial peptide transport
Abstract
The synthesis of peptides useful for the investigation of microbial peptide transport is reported. These peptides, L-alanyl-L-2-thiophenylglycine (Ala-α-TPG), L-alanyl-L-2-thiophenylglycyl-L-alanine (Ala-α-TPG-Ala) and L-alanyl-L-alanyl-L-2-thiophenylglycine (Ala-Ala-α-TPG), contain a phenylthio group attached to the α carbon of glycine.