Volume 10, Issue 2 pp. 89-94
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STUDIES ON CYTOCHROME C:

XIII. Synthesis of the Protected Undecapeptide (Sequence 77–87) of Horse Heart Cytochrome c.*

Gianfranco Borin

Gianfranco Borin

Centro di Studi sui Biopolimeri del C.N.R., Istituto di Chimica Organica dell'Università di Padova, Padova, Italy

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Bruno Filippi

Bruno Filippi

Centro di Studi sui Biopolimeri del C.N.R., Istituto di Chimica Organica dell'Università di Padova, Padova, Italy

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Diego Stivanello

Diego Stivanello

Centro di Studi sui Biopolimeri del C.N.R., Istituto di Chimica Organica dell'Università di Padova, Padova, Italy

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Fernando Marchiori

Corresponding Author

Fernando Marchiori

Centro di Studi sui Biopolimeri del C.N.R., Istituto di Chimica Organica dell'Università di Padova, Padova, Italy

Institute of Organic Chemistry University of Padova Via Marzolo, 1 35100 Padova ItalySearch for more papers by this author
First published: August 1977
Citations: 2

The amino acid residues, except glycine, are of the L-configuration. For a simpler description L-designation for individual amino acid residues is omitted. For abbreviations see Moroder et al. (1977).

Abstract

A solution synthesis of Z-Gly-Thr-Lys (Tfa)-Met-Ile-Phe-Ala-Gly-Ile-Lys (Tfa)-Lys (Tfa)-NHNH-Boc corresponding to the sequence 77–87 of horse heart cytochrome c is described. The protected undecapeptide was obtained from intermediate hepta- and tetrapeptide fragments by an azide coupling.

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