Focal liver diseases in neonatal and pediatric liver transplant candidates: a pictorial essay
Silvia Riva
Department of Medicine, Pediatric Hepatology, Istituto Mediterraneo Trapianti e Terapie ad Alta Specializzazione (IsMeTT), Palermo, Italy
Search for more papers by this authorSilvia Riva
Department of Medicine, Pediatric Hepatology, Istituto Mediterraneo Trapianti e Terapie ad Alta Specializzazione (IsMeTT), Palermo, Italy
Search for more papers by this authorAbstract
Caruso S, Mamone G, Marrone G, Milazzo M, Carollo V, Miraglia R, Maruzzelli L, Pasta A, Minervini MI, Spada M, Riva S, Luca A, Gridelli B. Focal liver diseases in neonatal and pediatric liver transplant candidates: a pictorial essay.Clin Transplant 2009: DOI: 10.1111/j.1399-0012.2009.01139.x© 2009 John Wiley & Sons A/S.
Abstract: The aim of this review is to present the wide spectrum of common and uncommon focal liver diseases affecting neonatal and pediatric liver transplant candidates, analyzed using ultrasonography (US), 16- or 64-multidetector row helical CT (MDCT) and 1.5-T magnetic resonance (MR) fast imaging. Correlation of imaging findings and explanted liver or histology is illustrated in representative cases. Associated uncommon congenital anomalies are shown.
References
- 1 Avila LF, Luis AL, Hernandez F et al. Liver transplantation for malignant tumours in children. Eur J Pediatr Surg 2006: 16: 411.
- 2 Meyers RL. Tumors of the liver in children. Surg Oncol 2007: 16: 195.
- 3 Emre S, McKenna GJ. Liver tumors in children. Pediatr Transplant 2004: 8: 632.
- 4 Comert S, Vitrinel A, Akin Y, Mutlu GY, Tokuc G, Bakir B. Abdominal mass in a neonate: hepatoblastoma. Indian J Pediatr 2007: 74: 956.
- 5 Van Tornout JM, Buckley JD, Quinn JJ et al. Timing and magnitude of decline in alpha-fetoprotein levels in treated children with unresectable or metastatic hepatoblastoma are predictors of outcome: a report from the Children’s Cancer Group. J Clin Oncol 1997: 15: 1190.
- 6 Roebuck DJ, Aronson D, Clapuyt P et al. International Childhood Liver Tumor Strategy Group. 2005. PRETEXT: a revised staging system for primary malignant liver tumours of childhood developed by the SIOPEL group. Pediatr Radiol 2007: 37: 123.
- 7 Wang JD, Chang TK, Chen HC et al. Pediatric liver tumors: initial presentation, image finding and outcome. Pediatr Int 2007: 49: 491.
- 8 Czauderna P, Mackinlay G, Perilongo G et al. Liver Tumors Study Group of the International Society of Pediatric Oncology. Hepatocellular carcinoma in children: results of the first prospective study of the International Society of Pediatric Oncology group. J Clin Oncol 2002: 20: 2798.
- 9 Chen JC, Chen CC, Chen WJ, Lai HS, Hung WT, Lee PH. Hepatocellular carcinoma in children: clinical review and comparison with adult cases. J Pediatr Surg 1998: 33: 1350.
- 10 Sevmis S, Karakayali H, Ozçay F et al. Liver transplantation for hepatocellular carcinoma in children. Pediatr Transplant 2008: 12: 52.
- 11 Ito K. Hepatocellular carcinoma: conventional MRI findings including gadolinium-enhanced dynamic imaging. Eur J Radiol 2006: 58: 186.
- 12 Helmberger TK, Ros PR, Mergo PJ, Tomczak R, Reiser MF. Pediatric liver neoplasms: a radiologic-pathologic correlation. Eur Radiol 1999: 9: 1339.
- 13 Roos JE, Pfiffner R, Stallmach T, Stuckmann G, Marincek B, Willi U. Infantile hemangioendothelioma. Radiographics 2003: 23: 1649.
- 14 Mortelé KJ, Vanzieleghem B, Mortelé B, Benoit Y, Ros PR. Solitary hepatic infantile hemangioendothelioma: dynamic gadolinium-enhanced MR imaging findings. Eur Radiol 2002: 12: 862.
- 15 Walsh R, Harrington J, Beneck D, Ozkaynak MF. Congenital infantile hepatic hemangioendothelioma type II treated with orthotopic liver transplantation. J Pediatr Hematol Oncol 2004: 26: 121.
- 16 Isaacs H Jr. Fetal and neonatal hepatic tumors. J Pediatr Surg 2007: 42: 1797.
- 17 Goodman P, Dominguez R, Castillo M. Diffuse neonatal hemangiomatosis: imaging findings in two patients. Comput Med Imaging Graph 1992: 16: 117.
- 18 Mehrabi A, Kashfi A, Fonouni H et al. Primary malignant hepatic epithelioid hemangioendothelioma: a comprehensive review of the literature with emphasis on the surgical therapy. Cancer 2006: 107: 2108.
- 19 Lyburn ID, Torreggiani WC, Harris AC et al. Hepatic epithelioid hemangioendothelioma: sonographic, CT, and MR imaging appearances. AJR Am J Roentgenol 2003: 180: 1359.
- 20 Stringer MD. The role of liver transplantation in the management of the paediatric liver tumors. Ann R Coll Surg Engl 2007: 89: 12.
- 21 Barthelmes L, Tait IS. Liver cell adenoma and liver cell adenomatosis. HPB (Oxford) 2005: 7: 186.
- 22 Ribeiro A, Burgart LJ, Nagorney DM, Gores GJ. Management of liver adenomatosis: results with a conservative surgical approach. Liver Transpl Surg 1998: 4: 388.
- 23 Grazioli L, Federle MP, Brancatelli G, Ichikawa T, Olivetti L, Blachar A. Hepatic adenomas: imaging and pathologic findings. Radiographics 2001: 21: 877.