Volume 65, Issue 10 pp. 1212-1221

Development and implementation of guidelines in allergic rhinitis – an ARIA-GA2LEN paper

J. Bousquet

J. Bousquet

University Hospital, Hôpital Arnaud de Villeneuve, Montpellier, and INSERM, CESP Centre for Research in Epidemiology and Population Health, U1018, Villejuif, France

Edited by: Thomas Bieber

Search for more papers by this author
H. J. Schünemann

H. J. Schünemann

Department of Clinical Epidemiology and Biostatistics, and Department of Medicine, McMaster University, Hamilton, ON, Canada

Search for more papers by this author
T. Zuberbier

T. Zuberbier

Allergy Centre Charité, Charité– Universitätsmedizin Berlin, Berlin, Germany

Edited by: Thomas Bieber

Search for more papers by this author
C. Bachert

C. Bachert

Ghent University, Ghent, Belgium

Edited by: Thomas Bieber

Search for more papers by this author
C. E. Baena-Cagnani

C. E. Baena-Cagnani

Faculty of Medicine, Catholic University of Cordoba, Cordoba, Argentina and Faculty of Specialization – Respiratory Medicine, University of Genoa, Genoa, Italy

Search for more papers by this author
P. J. Bousquet

P. J. Bousquet

University Hospital, Nîmes, France

Edited by: Thomas Bieber

Search for more papers by this author
J. Brozek

J. Brozek

Department of Clinical Epidemiology and Biostatistics, and Department of Medicine, McMaster University, Hamilton, ON, Canada

Search for more papers by this author
G. W. Canonica

G. W. Canonica

Allergy & Respiratory Diseases Clinic, University of Genova, Genova, Italy

Edited by: Thomas Bieber

Search for more papers by this author
T. B. Casale

T. B. Casale

Creighton University, Omaha, NE, USA

Search for more papers by this author
P. Demoly

P. Demoly

University Hospital of Montpellier – Inserm U657, Hôpital Arnaud de Villeneuve, Montpellier, France

Edited by: Thomas Bieber

Search for more papers by this author
R. Gerth van Wijk

R. Gerth van Wijk

Section of Allergology, Department of Internal Medicine, Erasmus MC, Rotterdam, the Netherlands

Edited by: Thomas Bieber

Search for more papers by this author
K. Ohta

K. Ohta

Teikyo University School of Medicine, Tokyo, Japan

Search for more papers by this author
E. D. Bateman

E. D. Bateman

Health Sciences Faculty, University of Cape Town, Cape Town, South Africa

Search for more papers by this author
M. Calderon

M. Calderon

Allergy Unit, Imperial College, London, UK

Edited by: Thomas Bieber

Search for more papers by this author
A. A. Cruz

A. A. Cruz

Faculdade de Medicina da Bahia, UFBA, and CNPq, Bahia, Brazil

Search for more papers by this author
W. K. Dolen

W. K. Dolen

Medical College of Georgia, Augusta, GA, USA

Search for more papers by this author
J. Haughney

J. Haughney

University of Aberdeen, Aberdeen, UK

Search for more papers by this author
R. F. Lockey

R. F. Lockey

Division of Allergy and Immunology, University of South Florida College of Medicine, Tampa, FL, USA

Search for more papers by this author
J. Lötvall

J. Lötvall

University of Gothenburg, Gothenburg, Sweden

Edited by: Thomas Bieber

Search for more papers by this author
P. O’Byrne

P. O’Byrne

McMaster University, Hamilton, ON, Canada

Search for more papers by this author
O. Spranger

O. Spranger

EFA (European Federation of Allergy and Airways Diseases Patients Associations), Brussels, Belgium

Edited by: Thomas Bieber

Search for more papers by this author
A. Togias

A. Togias

National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA

Search for more papers by this author
S. Bonini

S. Bonini

Second University of Naples, INMM-CNR, Rome, Italy

Edited by: Thomas Bieber

Search for more papers by this author
L. P. Boulet

L. P. Boulet

Institut de cardiologie et de pneumologie de l’Hôpital Laval and Université Laval, Laval, QC, Canada

Search for more papers by this author
P. Camargos

P. Camargos

Medical School, University Hospital, Federal University of Minas Gerais, Minas Gerais, Brazil

Search for more papers by this author
K. H. Carlsen

K. H. Carlsen

Department of Paediatrics, Ullevål University Hospital and The Faculty of Medicine, University of Oslo, Oslo, Norway

Edited by: Thomas Bieber

Search for more papers by this author
N. H. Chavannes

N. H. Chavannes

Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, the Netherlands

Edited by: Thomas Bieber

Search for more papers by this author
L. Delgado

L. Delgado

Faculdade de Medicina, University of Porto, Porto, Portugal

Edited by: Thomas Bieber

Search for more papers by this author
S. R. Durham

S. R. Durham

National Heart and Lung Institute, Imperial College, London, UK

Edited by: Thomas Bieber

Search for more papers by this author
W. J. Fokkens

W. J. Fokkens

Academic Medical Center, Amsterdam, the Netherlands

Edited by: Thomas Bieber

Search for more papers by this author
J. Fonseca

J. Fonseca

Allergy, Hospital S. Joao & Instituto, CUF; CINTESIS, Porto University Medical School, Porto, Portugal

Edited by: Thomas Bieber

Search for more papers by this author
T. Haahtela

T. Haahtela

Skin and Allergy Hospital, Helsinki University Hospital, Helsinki, Finland

Edited by: Thomas Bieber

Search for more papers by this author
O. Kalayci

O. Kalayci

Pediatric Allergy and Asthma Unit, Hacettepe, Ankara, Turkey

Search for more papers by this author
M. L. Kowalski

M. L. Kowalski

Department of Immunology, Rheumatology and Allergy, Medical University of Lodz, Lodz, Poland

Edited by: Thomas Bieber

Search for more papers by this author
D. Larenas-Linnemann

D. Larenas-Linnemann

Allergy Department, Hospital Médica Sur, Mexico city, Mexico

Search for more papers by this author
J. Li

J. Li

Guangzhou Institute of Respiratory Diseases, The First Affiliated Hospital of Guangzhou Medical School, Guangzhou, China

Search for more papers by this author
Y. Mohammad

Y. Mohammad

Tishreen University School of Medicine, Lattakia, Syria

Search for more papers by this author
J. Mullol

J. Mullol

Hospital Clínic i Universitari, IDIBAPS, CIBERES. Barcelona, Catalonia, Spain

Edited by: Thomas Bieber

Search for more papers by this author
R. Naclerio

R. Naclerio

University of Chicago, Chicago, IL, USA

Search for more papers by this author
R. E. O’Hehir

R. E. O’Hehir

Alfred Hospital and Monash University, Melbourne, Vic., Australia

Search for more papers by this author
N. Papadopoulos

N. Papadopoulos

Allergy Research Center, University of Athens, Athens, Greece

Edited by: Thomas Bieber

Search for more papers by this author
G. Passalacqua

G. Passalacqua

Allergy & Respiratory Diseases Clinic, University of Genova, Genova, Italy

Edited by: Thomas Bieber

Search for more papers by this author
K. F. Rabe

K. F. Rabe

Department of Pulmonology, Leiden University Medical Center, Leiden, the Netherlands

Edited by: Thomas Bieber

Search for more papers by this author
R. Pawankar

R. Pawankar

Nippon Medical School, Bunkyo-ku, Tokyo, Japan

Search for more papers by this author
D. Ryan

D. Ryan

Woodbrook Medical Centre, Loughborough, England And University of Aberdeen, Aberdeen, UK

Search for more papers by this author
B. Samolinski

B. Samolinski

Medical University of Warsaw, Warsaw, Poland

Search for more papers by this author
F. E. R. Simons

F. E. R. Simons

University of Manitoba, Winnipeg, MB, Canada

Search for more papers by this author
E. Valovirta

E. Valovirta

Terveystalo Turku, Turku, Finland

Edited by: Thomas Bieber

Search for more papers by this author
A. Yorgancioglu

A. Yorgancioglu

Celal Bayar University School of Medicine Department of Pulmonology, Manisa, Turkey

Search for more papers by this author
O. M. Yusuf

O. M. Yusuf

The Allergy & Asthma Institute, Islamabad, Pakistan

Search for more papers by this author
I. Agache

I. Agache

Transylvania University, Brasov, Romania

Search for more papers by this author
N. Aït-Khaled

N. Aït-Khaled

The Union, Paris, France

Search for more papers by this author
I. Annesi-Maesano

I. Annesi-Maesano

EPAR U707 INSERM and EPAR UMR-S UPMC, Paris, France

Search for more papers by this author
B. Beghe

B. Beghe

Department of Oncology, Haematology and Respiratory Diseases, University of Modena and Reggio Emilia, Modena, Italy

Search for more papers by this author
A. Ben Kheder

A. Ben Kheder

Hopital a Mami Ariana, Ariana, Tunisia

Search for more papers by this author
M. S. Blaiss

M. S. Blaiss

University of Tennessee Health Science Center, Memphis, TN, USA

Search for more papers by this author
D. A. Boakye

D. A. Boakye

Noguchi Memorial Institute for Medical Research, College of Health Sciences, University of Ghana, Legon, Accra, Ghana

Search for more papers by this author
J. Bouchard

J. Bouchard

Université Laval, Laval, QC, and Hôpital de la Malbaie, la Malbaie, QC, Canada

Search for more papers by this author
P. G. Burney

P. G. Burney

National Heart & Lung Institute at Imperial College, London, UK

Search for more papers by this author
W. W. Busse

W. W. Busse

Professor of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA

Search for more papers by this author
M. Chan-Yeung

M. Chan-Yeung

University of British Columbia, Vancouver, BC, Canada

Search for more papers by this author
Y. Chen

Y. Chen

National Cooperative Group of Pediatric Research on Asthma, Asthma Clinic and Education Center of the Capital Institute of Pediatrics, Peking, China

Search for more papers by this author
A. G. Chuchalin

A. G. Chuchalin

Pulmonology Research Institute and Russian Respiratory Society, Moscow, Russia

Search for more papers by this author
D. J. Costa

D. J. Costa

Primary Care Department, Montpellier University, Montpellier, France

Search for more papers by this author
A. Custovic

A. Custovic

University of Manchester, Manchester, UK

Search for more papers by this author
R. Dahl

R. Dahl

Aarhus University Hospital, Aarhus, Denmark

Search for more papers by this author
J. Denburg

J. Denburg

AllerGen NCE, McMaster University, Hamilton, ON, Canada

Search for more papers by this author
H. Douagui

H. Douagui

Centre Hospitalo-Universitaire de Béni-Messous, Algiers, Algeria

Search for more papers by this author
R. Emuzyte

R. Emuzyte

Vilnius University Faculty of Medicine, Vilnius, Lithuania

Search for more papers by this author
L. Grouse

L. Grouse

University of Washington School of Medicine, Seattle, WA, USA

Search for more papers by this author
M. Humbert

M. Humbert

Hôpital Antoine-Béclère, Université Paris-Sud, Clamart, France

Search for more papers by this author
C. Jackson

C. Jackson

Bute Medical School, University of St Andrews, St Andrews, UK

Search for more papers by this author
S. L. Johnston

S. L. Johnston

National Heart and Lung Institute, Imperial College London, London, UK

Search for more papers by this author
M. A. Kaliner

M. A. Kaliner

Geo Washington University School of Medicine, Washington DC – Institute for Asthma and Allergy, Chevy Chase, MD, USA

Search for more papers by this author
P. K. Keith

P. K. Keith

McMaster University, Hamilton, ON, Canada

Search for more papers by this author
Y. Y. Kim

Y. Y. Kim

Seoul National University Hospital, Seoul, Korea

Search for more papers by this author
J. M. Klossek

J. M. Klossek

University of Poitiers, Poitiers, France

Search for more papers by this author
P. Kuna

P. Kuna

Barlicki University Hospital, Medical University of Lodz, Lodz, Poland

Search for more papers by this author
L. T. Le

L. T. Le

University of Medicine and Pharmacy, Hochiminh City, Vietnam

Search for more papers by this author
C. Lemiere

C. Lemiere

Hôpital du Sacré-Coeur de Montréal and University of Montreal, Montreal, QC, Canada

Search for more papers by this author
B. Lipworth

B. Lipworth

University of Dundee, Dundee, UK

Search for more papers by this author
B. Mahboub

B. Mahboub

University of Sharjah, Sharjah, UAE

Search for more papers by this author
J. L. Malo

J. L. Malo

Hôpital du Sacré-Coeur de Montréal and University of Montreal, Montreal, QC, Canada

Search for more papers by this author
G. D. Marshall

G. D. Marshall

University of Mississippi, Jackson, MS, USA

Search for more papers by this author
S. Mavale-Manuel

S. Mavale-Manuel

Children’s Hospital, Maputo, Mozambique

Search for more papers by this author
E. O. Meltzer

E. O. Meltzer

Allergy & Asthma Medical Group & Research Center, University of California, San Diego, CA, USA

Search for more papers by this author
M. Morais-Almeida

M. Morais-Almeida

Immunoallergy Department, CUF-Descobertas Hospital, Lisbon, Portugal

Search for more papers by this author
C. Motala

C. Motala

School of Child and Adolescent Health, UCT and Red Cross War Memorial Children's Hospital, Cape Town, South Africa

Search for more papers by this author
C. Naspitz

C. Naspitz

Federal University of São Paulo, São Paulo, Brazil

Search for more papers by this author
K. Nekam

K. Nekam

Hospital of the Hospitaller Brothers in Buda, Budapest, Hungary

Search for more papers by this author
B. Niggemann

B. Niggemann

German Red Cross Hospital Berlin, Berlin, Germany

Search for more papers by this author
E. Nizankowska-Mogilnicka

E. Nizankowska-Mogilnicka

Jagiellonian University School of Medicine, Krakow, Poland

Edited by: Thomas Bieber

Search for more papers by this author
Y. Okamoto

Y. Okamoto

Chiba University, Chiba, Japan

Search for more papers by this author
M. P. Orru

M. P. Orru

Pharmacist, Italy

Search for more papers by this author
S. Ouedraogo

S. Ouedraogo

Centre Hospitalier Universitaire Pédiatrique Charles de Gaulle, Ouagadougou, Burkina Faso, West Africa

Search for more papers by this author
S. Palkonen

S. Palkonen

EFA European Federation of Allergy and Airways Diseases Patients’ Associations, Brussels, Belgium

Search for more papers by this author
T. A. Popov

T. A. Popov

Clinic of Allergy and Asthma, Medical University Sofia, Sofia, Bulgaria

Search for more papers by this author
D. Price

D. Price

University of Aberdeen, Aberdeen, UK

Search for more papers by this author
J. Rosado-Pinto

J. Rosado-Pinto

Immunoallergy Department, Hospital da Luz, Lisboa, Portugal

Search for more papers by this author
G. K. Scadding

G. K. Scadding

Royal National TNE Hospital, London, UK

Search for more papers by this author
T. M. Sooronbaev

T. M. Sooronbaev

National Centre Cardiology and Internal Medicine, Bishkek, Kyrgyzstan

Search for more papers by this author
S. W. Stoloff

S. W. Stoloff

University of Nevada School of Medicine, Reno, NV, USA

Search for more papers by this author
E. Toskala

E. Toskala

Finnish Institute of Occupational Health, Helsinki, Finland

Search for more papers by this author
P. Van Cauwenberge

P. Van Cauwenberge

Ghent University, Ghent, Belgium

Search for more papers by this author
O. Vandenplas

O. Vandenplas

University Hospital of Mont-Godinne, Catholic University of Louvain, Yvoir, Belgium

Search for more papers by this author
C. Van Weel

C. Van Weel

Department of Primary and Community Care, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands

Search for more papers by this author
G. Viegi

G. Viegi

CNR Institutes of Biomedicine and Molecular Immunology (IBIM), Palermo, and of Clinical Physiology (IFC), Pisa, Italy

Search for more papers by this author
J. C. Virchow

J. C. Virchow

University of Rostock, Rostock, Germany

Search for more papers by this author
D. Y. Wang

D. Y. Wang

Yong Loo Lin School of Medicine, National University of Singapore, Singapore

Search for more papers by this author
M. Wickman

M. Wickman

Sachs’ Children’s Hospital, Stockholm, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden

Search for more papers by this author
D. Williams

D. Williams

School of Pharmacy, University of North Carolina, Chapel Hill, NC, USA

Search for more papers by this author
B. P. Yawn

B. P. Yawn

Olmsted Medical Center, University of Minnesota, Rochester, MN, USA

Search for more papers by this author
H. J. Zar

H. J. Zar

Department of Paediatrics and Child Health, University of Cape Town, Cape Town, South Africa

Search for more papers by this author
M. Zernotti

M. Zernotti

Faculty of Medicine, Catholic University of Córdoba, Córdoba, Argentina

Search for more papers by this author
N. Zhong

N. Zhong

Guangzhou Institute of Respiratory Diseases, Guangzhou, China

Search for more papers by this author
In collaboration with the WHO Collaborating Center of Asthma and Rhinitis (Montpellier)

In collaboration with the WHO Collaborating Center of Asthma and Rhinitis (Montpellier)

University Hospital, Hôpital Arnaud de Villeneuve, Montpellier, and INSERM, CESP Centre for Research in Epidemiology and Population Health, U1018, Villejuif, France

Search for more papers by this author
First published: 07 September 2010
Citations: 82
Professor Jean Bousquet, MD, PhD, Service des Maladies Respiratoires, Hôpital Arnaud de Villeneuve, 371, avenue Doyen Gaston Giraud, F-34295 Montpellier Cedex 5, France.
Tel.: +33-467-33-61-05
Fax: +33-467-41-67-01
E-mail: [email protected]

Members of GA2LEN (Global Allergy and Asthma European Network), supported by the Sixth EU Framework program for research, contract n° FOOD-CT-2004-506378.

Abstract

To cite this article: Bousquet J, Schünemann HJ, Zuberbier T, Bachert C, Baena-Cagnani CE, Bousquet PJ, Brozek J, Canonica GW, Casale TB, Demoly P, Gerth van Wijk R, Ohta K, Bateman ED, Calderon M, Cruz AA, Dolen WK, Haughney J, Lockey RF, Lötvall J, O’Byrne P, Spranger O, Togias A, Bonini S, Boulet LP, Camargos P, Carlsen KH, Chavannes NH, Delgado L, Durham SR, Fokkens WJ, Fonseca J, Haahtela T, Kalayci O, Kowalski ML, Larenas-Linnemann D, Li J, Mohammad Y, Mullol J, Naclerio R, O’Hehir RE, Papadopoulos N, Passalacqua G, Rabe KF, Pawankar R, Ryan D, Samolinski B, Simons FER, Valovirta E, Yorgancioglu A, Yusuf OM, Agache I, Aït-Khaled N, Annesi-Maesano I, Beghe B, Ben Kheder A, Blaiss MS, Boakye DA, Bouchard J, Burney PG, Busse WW, Chan-Yeung M, Chen Y, Chuchalin AG, Costa DJ, Custovic A, Dahl R, Denburg J, Douagui H, Emuzyte R, Grouse L, Humbert M, Jackson C, Johnston SL, Kaliner MA, Keith PK, Kim YY, Klossek JM, Kuna P, Le LT, Lemiere C, Lipworth B, Mahboub B, Malo JL, Marshall GD, Mavale-Manuel S, Meltzer EO, Morais-Almeida M, Motala C, Naspitz C, Nekam K, Niggemann B, Nizankowska-Mogilnicka E, Okamoto Y, Orru MP, Ouedraogo S, Palkonen S, Popov TA, Price D, Rosado-Pinto J, Scadding GK, Sooronbaev TM, Stoloff SW, Toskala E, van Cauwenberge P, Vandenplas O, van Weel C, Viegi G, Virchow JC, Wang DY, Wickman M, Williams D, Yawn BP, Zar HJ, Zernotti M, Zhong N, In collaboration with the WHO Collaborating Center of Asthma and Rhinitis (Montpellier). Development and implementation of guidelines in allergic rhinitis – an ARIA-GA2LEN paper. Allergy 2010; 65: 1212–1221.

The links between asthma and rhinitis are well characterized. The Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines stress the importance of these links and provide guidance for their prevention and treatment. Despite effective treatments being available, too few patients receive appropriate medical care for both diseases. Most patients with rhinitis and asthma consult primary care physicians and therefore these physicians are encouraged to understand and use ARIA guidelines. Patients should also be informed about these guidelines to raise their awareness of optimal care and increase control of the two related diseases. To apply these guidelines, clinicians and patients need to understand how and why the recommendations were made. The goal of the ARIA guidelines is to provide recommendations about the best management options for most patients in most situations. These recommendations should be based on the best available evidence. Making recommendations requires the assessment of the quality of available evidence, deciding on the balance between benefits and downsides, consideration of patients' values and preferences, and, if applicable, resource implications. Guidelines must be updated as new management options become available or important new evidence emerges. Transparent reporting of guidelines facilitates understanding and acceptance, but implementation strategies need to be improved.

The full text of this article hosted at iucr.org is unavailable due to technical difficulties.