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PHOTOCHEMOTHERAPY OF PSORIASIS
ULLA-BRITT NIETSCHE M.D.,
Corresponding Author
ULLA-BRITT NIETSCHE M.D.
Department of Dermatology, University Hospital, Trornsoe, Norway
2 Ulla-Britt Nietsche, M. D., Department of Dermatology, Malmo Allmanna Sjukhus, Malmo, Sweden.Search for more papers by this authorULLA-BRITT NIETSCHE M.D.,
Corresponding Author
ULLA-BRITT NIETSCHE M.D.
Department of Dermatology, University Hospital, Trornsoe, Norway
2 Ulla-Britt Nietsche, M. D., Department of Dermatology, Malmo Allmanna Sjukhus, Malmo, Sweden.Search for more papers by this authorAbstract
ABSTRACT: Orally administered 8-methoxypsoralen followed by irradiation with longwave ultraviolet light (UVA, 320–400 nm, maximum 365 nm) resulted in 90–100% clearing in 24 of 26 psoriasis patients. Recurrence could be prevented by maintenance treatment. The treatment was tolerated well; no serious side effects were observed. A moderate increase of serum transaminase values was observed in 6 patients; in 5, these values became normal in a short time. The connection between these enzyme increases and the treatment is uncertain. At completion of the treatment the skin is universally, evenly hyperpigmented—a side effect considered positive by the patients.
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