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Absorption kinetics and bioavailability of phenobarbital after oral administration to dogs
F. AL-TAHAN,
H.-H. FREY,
F. AL-TAHAN
Laboratory of Pharmacology and Toxicology, School of Veterinary Medicine, Free University of Berlin, West Berlin, Germany
Search for more papers by this authorCorresponding Author
H.-H. FREY
Laboratory of Pharmacology and Toxicology, School of Veterinary Medicine, Free University of Berlin, West Berlin, Germany
Laboratory of Pharmacology and Toxicology, School, of Veterinary Medicine, Free University of Berlin, Koserstrasse 20, D-1000 Berlin-West 33, West Germany.Search for more papers by this authorF. AL-TAHAN,
H.-H. FREY,
F. AL-TAHAN
Laboratory of Pharmacology and Toxicology, School of Veterinary Medicine, Free University of Berlin, West Berlin, Germany
Search for more papers by this authorCorresponding Author
H.-H. FREY
Laboratory of Pharmacology and Toxicology, School of Veterinary Medicine, Free University of Berlin, West Berlin, Germany
Laboratory of Pharmacology and Toxicology, School, of Veterinary Medicine, Free University of Berlin, Koserstrasse 20, D-1000 Berlin-West 33, West Germany.Search for more papers by this author
REFERENCES
- Baggot, J.D. (1977) Principles of Drug Disposition in Domestic Animals. W. B. Saunders, Philadelphia , London , Toronto .
- Bochner, F., Carruthers, G., Kampmann, J. & Steiner, J. (1978) Handbook of Clinical Pharmacology, pp. 250–252. Little, Brown and Co., Boston .
- Eadie, M.J. & Tyrer, J.H. (1980) Anticonvulsant Therapy: Pharmacological Basis and Practice, 2nd edn. pp. 166–167. Churchill Livingstone, Edinburgh , London , New York .
- Frey, H.-H., Göbel W. & Löscher, W. (1979) Pharmacokinetics of primidone and its active metabolites in the dog. Archives Internationales de Pharmacodynamie et de Thérapie, 242, 14–30.
- Frey, H.-H., Kampmann, E. & Kaergaard Nielsen, C. (1968) Study on combined treatment with phenobarbital and diphenylhydantoin. Acta Pharmacologica et Toxicologica, 26, 284–292.
- Frey, H.-H. & Loscher, W. (1980a) Clinical pharmacokinetics of phenytoin in the dog: a reevaluation. American Journal of Veterinary Research, 41, 1635–1638.
- Frey, H.-H. & Löscher, W. (1980b) Pharmacokinetics of carbamazepine in the dog. Archives Internationales de Pharmacodynamie et 'de Thérapie, 243, 180–191.
- Löscher, W. (1978) Serum protein binding and pharmacokinetics of valproate in man, dog, rat and mouse. Journal of Pharmacology and Experimental Therapeutics, 204, 255–261.
- Löscher, W. (1981) Plasma levels of valproic acid and its metabolites during continued treatment in dogs. Journal of Veterinary Pharmacology and Therapeutics, 4, 111–119.
- Löscher, W. & Esenwein, H. (1978) Pharmacokinetics of sodium valproate in dog and mouse. Arzneimittel-Forschung, 28, 282–287.
- Löscher, W. & Göbel, W. (1979) Consecutive gas chromatographic determination of phenytoin, phenobarbital, primidone, phenylethylmalonamide, carbamazepine, trimethadione, dimethadione, ethosuximide, and valproate from the same serum specimen. Epilépsia, 19, 463–473.
- Svensmark, O. & Buchthal, F. (1963) Accumulation of phenobarbital in man. Epilepsia, 4, 199–206.
- Wagner, J.G. (1975) Fundamentals of Clinical Pharmacokinetics. Drug Intelligence Publications Inc., Hamilton , Illinois .
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