Volume 20, Issue 6 pp. 468-470
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Serum sickness-like illness following streptokinase therapy. A case report

J.D. CREAMER

Corresponding Author

J.D. CREAMER

St John's Institute of Dermatology, St Thomas' Hospital, London UK

Dr J.D. Creamer, St John's Institute of Dermatology, St Thomas' Hospital, Lambeth Palace Road, London SE1 7EH, UK.Search for more papers by this author
J.A. MCGRATH

J.A. MCGRATH

St John's Institute of Dermatology, St Thomas' Hospital, London UK

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M. WEBB-PEPLOE

M. WEBB-PEPLOE

Department of Cardiology, St Thomas' Hospital, London UK

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N.P. SMITH

N.P. SMITH

St John's Institute of Dermatology, St Thomas' Hospital, London UK

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First published: November 1995
Citations: 2

Summary

We report a patient who developed a serum sickness-like illness characterized by fever, arthritis, haematuria and a purpuric eruption 7 days following streptokinase therapy for myocardial infarction. Blood tests demonstrated increased circulating immune complexes. The skin involvement resulted in extensive, painful cutaneous infarction with secondary bacterial infection. Serum sickness is an uncommon but recognized complication of streptokinase therapy.

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