Clinical and Experimental Dermatology
Volume 8, Issue 6 pp. 613-617
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The effect of UV irradiation and photochemotherapy (PUVA) on histamine weal and flare in human skin

R.E. ASHTON, 

R.E. ASHTON

St John's Hospital for Diseases of the Skin, 5 Lisle Street, Leicester Square, London wc 2 h 7 bj and Institute of Dermatology, Homerton Grave, London e 9 6 bx

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M.W. GREAVES, 

Corresponding Author

M.W. GREAVES

St John's Hospital for Diseases of the Skin, 5 Lisle Street, Leicester Square, London wc 2 h 7 bj and Institute of Dermatology, Homerton Grave, London e 9 6 bx

Professor M.W. Greaves, SE John's Hospital for Diseases of the Skin, 5 Lisle Street, Leicester Square, London WC2H 7BJ.Search for more papers by this author
First published: November 1983
https://doi.org/10.1111/j.1365-2230.1983.tb01830.x
Citations: 8

Summary

It is recognized that ultraviolet light has a beneficial effect in various inflammatory disorders of the skin. We have used histamine weal and flare as a model testing the effect of ultraviolet light on vascular response. No difference in weal and flare reaction following intradermal injection of 0·01-10·0 μg of hisiamine was found between covered and exposed skin following UV radiation or photochemotherapy (PUVA).

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