Volume 114, Issue 3 pp. 349-351
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IgG subclasses in acne vulgaris

D.B. HOLLAND

D.B. HOLLAND

University Department of Immunology, The General Infirmary, Leeds LS1 3EX, U.K.

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E. INGHAM

E. INGHAM

University Department of Immunology, The General Infirmary, Leeds LS1 3EX, U.K.

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G. GOWLAND

G. GOWLAND

University Department of Immunology, The General Infirmary, Leeds LS1 3EX, U.K.

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W.J. CUNLIFFE

W.J. CUNLIFFE

University Department of Dermatology, The General Infirmary, Leeds LS1 3EX, U.K.

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First published: March 1986
Citations: 14

SUMMARY

IgG subclasses were measured in male patients with very low grade or severe acne. No IgG subclass deficiencies were found. Patients with severe acne had a significant increase in total IgG attributable to their exposure to antigens which stimulate the production of antibodies in the IgG2 and IgG3 subclasses.

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