Experimental Trichophyton infection of intact human skin

A simple new method of producing experimental Trichophyton rubrum infection in man is discussed. A suspension of fresh culture using a granular colony was applied under occlusion on areas of skin. Occlusion was removed after 5 days and a semi-occlusive dressing applied. It was possible to induce typical ringed or discoid lesions, which could persist for a long time if semi-occlusive dressings were continuously applied.