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Comparison of Antibody Titers against Borrelial Strains Isolated in Japan by the Microcapsule Agglutination Test for Serological Studies of Early Lyme Disease

Corresponding Author

Yoshiko Arimitsu

Department of Microbiology, National Institute of Health, Shinjuku-ku, Tokyo, 162 Japan

Address correspondence to Dr. Yoshiko Arimitsu, Department of Microbiology, National Institute of Health, Toyama 1-23-1, Shinjuku-ku, Tokyo 162, Japan.Search for more papers by this author

Masaaki Seki,

Masaaki Seki

Japan Lyophilization Laboratories, Kiyose, Tokyo, 204 Japan

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Minoru Nakao,

Minoru Nakao

Department of Parasitology, Asahikawa Medical College, Asahikawa, Hokkaido, 078 Japan

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Kenji Miyamoto,

Kenji Miyamoto

Department of Parasitology, Asahikawa Medical College, Asahikawa, Hokkaido, 078 Japan

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Yoshiko Arimitsu,

Corresponding Author

Yoshiko Arimitsu

Department of Microbiology, National Institute of Health, Shinjuku-ku, Tokyo, 162 Japan

Address correspondence to Dr. Yoshiko Arimitsu, Department of Microbiology, National Institute of Health, Toyama 1-23-1, Shinjuku-ku, Tokyo 162, Japan.Search for more papers by this author

Masaaki Seki,

Masaaki Seki

Japan Lyophilization Laboratories, Kiyose, Tokyo, 204 Japan

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Minoru Nakao,

Minoru Nakao

Department of Parasitology, Asahikawa Medical College, Asahikawa, Hokkaido, 078 Japan

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Kenji Miyamoto,

Kenji Miyamoto

Department of Parasitology, Asahikawa Medical College, Asahikawa, Hokkaido, 078 Japan

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First published: April 1994

https://doi.org/10.1111/j.1348-0421.1994.tb01775.x

Citations: 1

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Abstract

Results of a passive microcapsule agglutination test using 2 Japanese strains, Borrelia garinii and Borrelia afzelii, were comparable to that of the passive microcapsule agglutination test using a Swiss strain Borrelia burgdorferi IRS in detecting antibodies of an early stage of Lyme disease patients in Japan. MCAT with microcapsule sensitized strain IRS seems likely to become one of the important tools for the early diagnosis of Lyme disease in the world. The highest titer of MCAT was detected in the serum samples of patients which were taken around 2 weeks after erythema chronicum migrans. The test is very simple and can be employed easily in diagnostic laboratories.

Abbreviations

ECM: Erythema chronicum migrans
MAT: Microscopic agglutination test
MC: Microcapsule
MCAT: Microcapsule agglutination test.

References

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Volume38, Issue4

April 1994

Pages 269-272

Comparison of Antibody Titers against Borrelial Strains Isolated in Japan by the Microcapsule Agglutination Test for Serological Studies of Early Lyme Disease

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Comparison of Antibody Titers against Borrelial Strains Isolated in Japan by the Microcapsule Agglutination Test for Serological Studies of Early Lyme Disease

Abstract

Abbreviations

References

Citing Literature

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