Original Article

Neonatal Lupus Erythematosus Occurring in Identical Twins

Corresponding Author

Masako Shimosegawa

Department of Dermatology, Iwate Medical University, 19–1 Uchimaru, Morioka 020, Japan

Reprint requests to: Masako Shimosegawa, M.D., Department of Dermatology, Iwate Medical University, 19-1 Uchimaru, Morioka 020, Japan.Search for more papers by this author

Toshihide Akasaka,

Toshihide Akasaka

Department of Dermatology, Iwate Medical University, 19–1 Uchimaru, Morioka 020, Japan

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Mayumi Matsuta,

Mayumi Matsuta

Department of Dermatology, Iwate Medical University, 19–1 Uchimaru, Morioka 020, Japan

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Masako Shimosegawa,

Corresponding Author

Masako Shimosegawa

Department of Dermatology, Iwate Medical University, 19–1 Uchimaru, Morioka 020, Japan

Reprint requests to: Masako Shimosegawa, M.D., Department of Dermatology, Iwate Medical University, 19-1 Uchimaru, Morioka 020, Japan.Search for more papers by this author

Toshihide Akasaka,

Toshihide Akasaka

Department of Dermatology, Iwate Medical University, 19–1 Uchimaru, Morioka 020, Japan

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Mayumi Matsuta,

Mayumi Matsuta

Department of Dermatology, Iwate Medical University, 19–1 Uchimaru, Morioka 020, Japan

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First published: 09 April 2015

https://doi.org/10.1111/j.1346-8138.1997.tb02296.x

Citations: 14

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Abstract

The patients were one-month-old identical twins. Scaly erythema was noted mainly on the trunk, face, and scalp of one twin starting about three weeks after birth and starting about two weeks after birth in the other. The patients' courses were observed without treatment; the eruptions tended to disappear two months after birth. The mother had a past history of transient facial erythema. Both twins and mother were positive for anti-nuclear antibody, anti-SS-A antibody, and anti-SS-B antibody. The histopathological findings corresponded to those of discoid lupus erythematosus (DLE). The class of HLA typing revealed Cw3 in both twins, which is frequently observed in neonatal lupus erythematosus (NLE), and A24 in the mother, which is frequently observed in mothers of babies with NLE.

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Volume24, Issue9

September 1997

Pages 578-582

Neonatal Lupus Erythematosus Occurring in Identical Twins

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Neonatal Lupus Erythematosus Occurring in Identical Twins

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