Environmental perceptions, mental performance, and physiological responses of people with respiratory allergies exposed to reduced Indoor Air Quality

To investigate the need of allergic population for indoor environment quality, exposure effects of poor air quality on subjects with respiratory allergies were compared with those on healthy people, including perceptual responses, health symptoms, mental performance, and physiological responses. The experimental intervention was with and without ventilation at thermally neutral rooms, creating two exposure conditions indicated by CO₂ concentration ranges of 502 to 3297 ppm (2438 ± 1527 ppm) and 517 to 5687 ppm (3615 ± 1527 ppm). 63 subjects (32 allergic subjects and 31 non-allergic subjects) were exposed to both conditions for 3 hours. The main results suggested that, compared with healthy people, people with respiratory allergy seem to be more sensitive or less acceptable to reduced air quality polluted by occupants during instantaneous exposure. Besides, the allergic group performed worse in cognitive tests than non-allergic group. After 3 hours of continuous exposure, people with respiratory allergy reported stronger intensity of respiratory irritations and seemed to suffer more inflammation indicated by a higher level of interleukin 1L-1β.