Volume 20, Issue 8 e70027
ORIGINAL RESEARCH

Differences across four major US urban areas in metabolic syndrome in the Hispanic Community Children's Health Study/Study of Latino Youth (SOL Youth)

Lauren Iacono

Lauren Iacono

Division of Pediatric Endocrinology and Diabetes, University of Vermont Medical Center, Larner College of Medicine at the University of Vermont, Burlington, Vermont, USA

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Paola Filigrana

Corresponding Author

Paola Filigrana

Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York, USA

Correspondence

Paola Filigrana, Department of Epidemiology and Population Health, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Belfer Building-Room 1308, Bronx, NY 10461, USA.

Email: [email protected]

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Monica Batalha

Monica Batalha

Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York, USA

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Krista M. Perreira

Krista M. Perreira

Department of Social Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA

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Linda C. Gallo

Linda C. Gallo

Department of Psychology, San Diego State University, San Diego, California, USA

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Bharat Thyagarajan

Bharat Thyagarajan

Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota, USA

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Martha L. Daviglus

Martha L. Daviglus

Institute for Minority Health Research, University of Illinois at Chicago, Chicago, Illinois, USA

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Amber Pirzada

Amber Pirzada

Institute for Minority Health Research, University of Illinois at Chicago, Chicago, Illinois, USA

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Alan M. Delamater

Alan M. Delamater

Department of Pediatrics, University of Miami, Miami, Florida, USA

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Frank J. Penedo

Frank J. Penedo

Department of Psychology, University of Miami, Miami, Florida, USA

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Kelly R. Evenson

Kelly R. Evenson

Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA

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Carmen R. Isasi

Carmen R. Isasi

Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York, USA

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First published: 19 May 2025

Lauren Iacono and Paola Filigrana contributed equally as first authors.

Summary

Background

Although Hispanic/Latino youth experience a high burden of cardiometabolic risk factors, few studies address regional differences.

Objective

We assessed differences between urban areas in metabolic syndrome and cardiometabolic markers among US Hispanic/Latino youth and examined underlying factors explaining these differences.

Methods

Cross-sectional study of youth (n = 1466, aged 8–16 years) in four US urban areas (Chicago, Bronx, Miami and San Diego) of the Hispanic Community Children's Health Study/Study of Latinos. Metabolic syndrome was ascertained following the International Diabetes Federation criteria. Socio-demographics, perceived environmental characteristics and diet quality were collected through questionnaires. Physical activity was measured using accelerometry. Survey regression models assessed the association between urban areas and metabolic syndrome.

Results

There were differences across urban areas in socio-demographic, behavioural and perceived environmental characteristics. Relative to youth in the four urban areas, youth in Chicago (odds ratios [OR]: 2.39, 95% confidence interval [CI]: 1.29, 4.42), but not Bronx and San Diego, had higher odds of metabolic syndrome, while youth in Miami had lower odds of this syndrome (OR: 0.32, 95% CI: 0.12, 0.85).

Conclusion

We found differences across US urban areas in metabolic syndrome in Hispanic/Latino youth. Although behavioural and environmental characteristics partially explained these differences, future research is needed to understand persistent differences.

CONFLICT OF INTEREST STATEMENT

No conflict of interest was declared.

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