Fixed orthodontic appliances cause pain and disturbance in somatosensory function
Huijie Shen
Orofacial Pain and TMD Research Unit, Institute of Stomatology, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, China
Institute of Stomatology and Department of Orthodontics, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, China
Search for more papers by this authorSheng Shao
Orofacial Pain and TMD Research Unit, Institute of Stomatology, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, China
Institute of Stomatology and Department of Orthodontics, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, China
Search for more papers by this authorJinglu Zhang
Orofacial Pain and TMD Research Unit, Institute of Stomatology, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, China
Search for more papers by this authorZhendong Wang
Orofacial Pain and TMD Research Unit, Institute of Stomatology, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, China
Institute of Stomatology and Department of Orthodontics, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, China
Search for more papers by this authorDong Lv
Orofacial Pain and TMD Research Unit, Institute of Stomatology, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, China
Institute of Stomatology and Department of Orthodontics, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, China
Search for more papers by this authorCorresponding Author
Wenjing Chen
Orofacial Pain and TMD Research Unit, Institute of Stomatology, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, China
Institute of Stomatology and Department of Orthodontics, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, China
Wenjing Chen, Orofacial Pain and TMD Research Unit, Institute of Stomatology, Affiliated Hospital of Stomatology, Nanjing Medical University, 136 Hanzhong Road, Nanjing (210029), China
E-mail: [email protected]
Search for more papers by this authorPeter Svensson
Section of Orofacial Pain and Jaw Function, School of Dentistry, Aarhus University, Aarhus, Denmark
Department of Dental Medicine, Karolinska Institute, Huddinge, Sweden
Search for more papers by this authorKelun Wang
Orofacial Pain and TMD Research Unit, Institute of Stomatology, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, China
Center for Sensory-Motor Interaction (SMI) Aalborg University, Aalborg, Denmark
Search for more papers by this authorHuijie Shen
Orofacial Pain and TMD Research Unit, Institute of Stomatology, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, China
Institute of Stomatology and Department of Orthodontics, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, China
Search for more papers by this authorSheng Shao
Orofacial Pain and TMD Research Unit, Institute of Stomatology, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, China
Institute of Stomatology and Department of Orthodontics, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, China
Search for more papers by this authorJinglu Zhang
Orofacial Pain and TMD Research Unit, Institute of Stomatology, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, China
Search for more papers by this authorZhendong Wang
Orofacial Pain and TMD Research Unit, Institute of Stomatology, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, China
Institute of Stomatology and Department of Orthodontics, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, China
Search for more papers by this authorDong Lv
Orofacial Pain and TMD Research Unit, Institute of Stomatology, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, China
Institute of Stomatology and Department of Orthodontics, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, China
Search for more papers by this authorCorresponding Author
Wenjing Chen
Orofacial Pain and TMD Research Unit, Institute of Stomatology, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, China
Institute of Stomatology and Department of Orthodontics, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, China
Wenjing Chen, Orofacial Pain and TMD Research Unit, Institute of Stomatology, Affiliated Hospital of Stomatology, Nanjing Medical University, 136 Hanzhong Road, Nanjing (210029), China
E-mail: [email protected]
Search for more papers by this authorPeter Svensson
Section of Orofacial Pain and Jaw Function, School of Dentistry, Aarhus University, Aarhus, Denmark
Department of Dental Medicine, Karolinska Institute, Huddinge, Sweden
Search for more papers by this authorKelun Wang
Orofacial Pain and TMD Research Unit, Institute of Stomatology, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, China
Center for Sensory-Motor Interaction (SMI) Aalborg University, Aalborg, Denmark
Search for more papers by this authorAbstract
This study aimed to assess the short-term effects of orthodontic pain on quantitative sensory testing (QST) in subjects receiving fixed orthodontic treatment. Twenty patients and 12 healthy volunteers (as controls) participated. All 20 patients had bonded AO self-ligating brackets, with a 0.014 super elastic nickel-titanium arch wire placed in the brackets. Pain [self-reported on a visual analog scale (VAS)], and thermal and mechanical thresholds, were tested at six time points – before (baseline), and 2 h, 24 h, 7 d, 14 d, and 30 d after, force application – in the treatment group. The attached gingiva adjacent to the left upper central incisor (21 gingiva) was hypersensitive to cold stimuli (i.e. increased cold detection thresholds were detected) in the treatment group. The pressure pain thresholds of the left upper central incisor (21) and 21 gingiva were significantly reduced. Our results suggest clear signs of sensitization of the trigeminal nociceptive system up to 1 month after force application and orthodontic pain. Quantitative assessment of somatosensory function may help to provide a better understanding and profiling of the underlying neurobiological mechanisms related to orthodontic pain.
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