Cerebrospinal and blood levels of amino acids as potential biomarkers for Parkinson's disease: review and meta-analysis. Response to letter to the editor by Zheng et al.
Corresponding Author
F. J. Jiménez-Jiménez
Section of Neurology, Hospital Universitario del Sureste, Arganda del Rey, Madrid, Spain
Correspondence: F. J. Jiménez-Jiménez, Section of Neurology, Hospital Universitario del Sureste, Arganda del Rey, C/Marroquina 14, 3º B, E-28030 Madrid, Spain (tel.: 34636968395; fax: +34913280704; e-mails: [email protected]; [email protected])
Contribution: Conceptualization (equal), Data curation (equal), Formal analysis (equal), Funding acquisition (equal), Investigation (equal), Methodology (equal), Project administration (equal), Resources (equal), Software (equal), Supervision (equal), Validation (equal), Visualization (equal), Writing - original draft (equal), Writing - review & editing (equal)
Search for more papers by this authorH. Alonso-Navarro
Section of Neurology, Hospital Universitario del Sureste, Arganda del Rey, Madrid, Spain
Contribution: Conceptualization (equal), Data curation (equal), Formal analysis (equal), Funding acquisition (equal), Investigation (equal), Methodology (equal), Project administration (equal), Resources (equal), Software (equal), Supervision (equal), Validation (equal), Visualization (equal), Writing - original draft (equal), Writing - review & editing (equal)
Search for more papers by this authorE. García-Martín
UNEx, ARADyAL Instituto de Salud Carlos III, University Institute of Molecular Pathology Biomarkers, Cáceres, Spain
Contribution: Conceptualization (equal), Data curation (equal), Formal analysis (equal), Funding acquisition (supporting), Investigation (equal), Methodology (equal), Project administration (equal), Resources (equal), Software (equal), Supervision (equal), Validation (equal), Visualization (equal), Writing - original draft (equal), Writing - review & editing (equal)
Search for more papers by this authorJ. A. G. Agúndez
UNEx, ARADyAL Instituto de Salud Carlos III, University Institute of Molecular Pathology Biomarkers, Cáceres, Spain
Contribution: Conceptualization (equal), Data curation (equal), Formal analysis (equal), Funding acquisition (supporting), Methodology (equal), Project administration (equal), Resources (equal), Software (equal), Supervision (equal), Validation (equal), Visualization (equal), Writing - original draft (equal), Writing - review & editing (equal)
Search for more papers by this authorCorresponding Author
F. J. Jiménez-Jiménez
Section of Neurology, Hospital Universitario del Sureste, Arganda del Rey, Madrid, Spain
Correspondence: F. J. Jiménez-Jiménez, Section of Neurology, Hospital Universitario del Sureste, Arganda del Rey, C/Marroquina 14, 3º B, E-28030 Madrid, Spain (tel.: 34636968395; fax: +34913280704; e-mails: [email protected]; [email protected])
Contribution: Conceptualization (equal), Data curation (equal), Formal analysis (equal), Funding acquisition (equal), Investigation (equal), Methodology (equal), Project administration (equal), Resources (equal), Software (equal), Supervision (equal), Validation (equal), Visualization (equal), Writing - original draft (equal), Writing - review & editing (equal)
Search for more papers by this authorH. Alonso-Navarro
Section of Neurology, Hospital Universitario del Sureste, Arganda del Rey, Madrid, Spain
Contribution: Conceptualization (equal), Data curation (equal), Formal analysis (equal), Funding acquisition (equal), Investigation (equal), Methodology (equal), Project administration (equal), Resources (equal), Software (equal), Supervision (equal), Validation (equal), Visualization (equal), Writing - original draft (equal), Writing - review & editing (equal)
Search for more papers by this authorE. García-Martín
UNEx, ARADyAL Instituto de Salud Carlos III, University Institute of Molecular Pathology Biomarkers, Cáceres, Spain
Contribution: Conceptualization (equal), Data curation (equal), Formal analysis (equal), Funding acquisition (supporting), Investigation (equal), Methodology (equal), Project administration (equal), Resources (equal), Software (equal), Supervision (equal), Validation (equal), Visualization (equal), Writing - original draft (equal), Writing - review & editing (equal)
Search for more papers by this authorJ. A. G. Agúndez
UNEx, ARADyAL Instituto de Salud Carlos III, University Institute of Molecular Pathology Biomarkers, Cáceres, Spain
Contribution: Conceptualization (equal), Data curation (equal), Formal analysis (equal), Funding acquisition (supporting), Methodology (equal), Project administration (equal), Resources (equal), Software (equal), Supervision (equal), Validation (equal), Visualization (equal), Writing - original draft (equal), Writing - review & editing (equal)
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References
- 1Zheng F, Zhou J, Wang C, Hu W, Krisckek B. There may be no significant increase of cerebrospinal fluid tyrosine levels in patients with Parkinson's disease. Eur J Neurol 2020; 28: e15–e16.
- 2Jiménez-Jiménez FJ, Alonso-Navarro H, García-Martín E, Agúndez JAG. Cerebrospinal and blood levels of amino acids as potential biomarkers for Parkinson's disease: review and meta-analysis. Eur J Neurol 2020; 27(11): 2336–2347.
- 3Tohgi H, Abe T, Takahashi S, Nozaki Y, Kikuchi T. Concentrations of tyrosine, L-dihydroxyphenylalanine, dopamine, and 3-O-methyldopa in the cerebrospinal fluid of Parkinson's disease. Neurosci Lett 1991; 127: 212–214.
- 4Mally J, Szalai G, Stone TW. Changes in the concentration of amino acids in serum and cerebrospinal fluid of patients with Parkinson's diseases. J Neurol Sci 1997; 151: 159–162.
