Volume 32, Issue 12 pp. 1876-1879
Case Report

Oral Everolimus for Treatment of a Giant Left Ventricular Rhabdomyoma in a Neonate—Rapid Tumor Regression Documented by Real Time 3D Echocardiography

Robert Wagner M.D., Ph.D.

Corresponding Author

Robert Wagner M.D., Ph.D.

Department of Pediatric Cardiology, University of Leipzig, Heart Center, Leipzig, Germany

Address for correspondence and reprint requests: Robert Wagner, M.D, Ph.D., Department of Paediatric Cardiology, Heart Centre, University of Leipzig, Strümpellstr. 39, D-04289 Leipzig, Germany. Fax: +49-341-865-1143;

E-mail: [email protected]

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Frank Thomas Riede M.D.

Frank Thomas Riede M.D.

Department of Pediatric Cardiology, University of Leipzig, Heart Center, Leipzig, Germany

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Hiroshi Seki M.D.

Hiroshi Seki M.D.

Department of Cardiac Surgery, University of Leipzig, Heart Center, Leipzig, Germany

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Frauke Hornemann M.D.

Frauke Hornemann M.D.

Department of Pediatric Neurology, University of Leipzig, Leipzig, Germany

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Steffen Syrbe M.D.

Steffen Syrbe M.D.

Department of Pediatric Neurology, University of Leipzig, Leipzig, Germany

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Ingo Daehnert M.D., Ph.D.

Ingo Daehnert M.D., Ph.D.

Department of Pediatric Cardiology, University of Leipzig, Heart Center, Leipzig, Germany

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Michael Weidenbach M.D., Ph.D.

Michael Weidenbach M.D., Ph.D.

Department of Pediatric Cardiology, University of Leipzig, Heart Center, Leipzig, Germany

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First published: 22 July 2015
Citations: 24
Funding Sources: None.
Ethics Approval: The authors warrant that the subject/patients’ rights and confidentiality have been well protected in all aspects. All relevant ethical safeguards have been met in relation to subject/patient protection. As this manuscript reports on a clinical case, approval from an ethics committee has not been obtained. As indicated in the manuscript, informed consent from the parents was obtained.

Abstract

The presented case reports on successful treatment with everolimus in a neonate with left ventricular giant rhabdomyoma. The authors used a different dosage regime compared to literature and documented rapid tumor regression by 3D echocardiography.

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