Development and preliminary testing of a brief clinical tool to enable daily monitoring of chemotherapy toxicity: The Daily Chemotherapy Toxicity self-Assessment Questionnaire
Corresponding Author
Roma Maguire
Department of Computer and Information Sciences, University of Strathclyde, Glasgow, UK
Correspondence
Roma Maguire, Department of Computer and Information Sciences, University of Strathclyde, Livingstone Tower, 26 Richmond Street, Glasgow G1 1XH, UK.
Email: [email protected]
Search for more papers by this authorGrigorios Kotronoulas
School of Medicine, Dentistry and Nursing, University of Glasgow, Glasgow, UK
Search for more papers by this authorPeter T. Donnan
Population Health Sciences, Medical Research Institute, University of Dundee, Dundee, UK
Search for more papers by this authorCatherine Paterson
School of Nursing and Midwifery, Robert Gordon University, Aberdeen, UK
Search for more papers by this authorLisa McCann
Department of Computer and Information Sciences, University of Strathclyde, Glasgow, UK
Search for more papers by this authorJohn Connaghan
Department of Computer and Information Sciences, University of Strathclyde, Glasgow, UK
Search for more papers by this authorDavid G. G. Di Domenico
School of Health, Wellbeing and Social Care, Faculty of Wellbeing, Education and Language Studies, The Open University, Edinburgh, UK
Search for more papers by this authorNora Kearney
School of Nursing, Midwifery and Health Systems, University College Dublin, Dublin, Ireland
Search for more papers by this authorCorresponding Author
Roma Maguire
Department of Computer and Information Sciences, University of Strathclyde, Glasgow, UK
Correspondence
Roma Maguire, Department of Computer and Information Sciences, University of Strathclyde, Livingstone Tower, 26 Richmond Street, Glasgow G1 1XH, UK.
Email: [email protected]
Search for more papers by this authorGrigorios Kotronoulas
School of Medicine, Dentistry and Nursing, University of Glasgow, Glasgow, UK
Search for more papers by this authorPeter T. Donnan
Population Health Sciences, Medical Research Institute, University of Dundee, Dundee, UK
Search for more papers by this authorCatherine Paterson
School of Nursing and Midwifery, Robert Gordon University, Aberdeen, UK
Search for more papers by this authorLisa McCann
Department of Computer and Information Sciences, University of Strathclyde, Glasgow, UK
Search for more papers by this authorJohn Connaghan
Department of Computer and Information Sciences, University of Strathclyde, Glasgow, UK
Search for more papers by this authorDavid G. G. Di Domenico
School of Health, Wellbeing and Social Care, Faculty of Wellbeing, Education and Language Studies, The Open University, Edinburgh, UK
Search for more papers by this authorNora Kearney
School of Nursing, Midwifery and Health Systems, University College Dublin, Dublin, Ireland
Search for more papers by this authorAbstract
Close monitoring of chemotherapy toxicity can be instrumental in ensuring prompt symptom management and quality care. Our aim was to develop a brief clinical tool to enable daily assessment of chemotherapy toxicity and investigate/establish its content validity, feasibility/applicability, internal consistency and stability. Development of the Daily Chemotherapy Toxicity self-Assessment Questionnaire (DCTAQ) was based on an initial item pool created from two scoping reviews. Expert panel review (n = 15) and cognitive debriefing with patients with cancer (n = 7) were used to establish content validity. Feasibility/acceptability, applicability (self-report vs. interview-like administration), internal consistency (KR-20) and test–retest reliability (at 1-hr intervals) of the DCTAQ were field-tested with 82 patients with breast or colorectal cancer receiving active chemotherapy at eight hospitals. Initial development/content validity stages enabled item revisions and re-wording that led to a final, 11-item DCTAQ version with 10 core symptom items plus one open-ended “any other symptom” item. Feasibility and acceptability were demonstrated through the absence of participant withdrawals, absence of missing data and no complaints about tool length. The DCTAQ was found to have modest internal consistency (KR-20 = 0.56), but very good test–retest reliability. The DCTAQ is a brief clinical tool that allows for rapid and accurate daily assessments of chemotherapy toxicity in clinical practice.
CONFLICTS OF INTEREST
The authors declare that there are no personal or financial conflicts of interest with regard to this work. The authors declare that they have full control of all primary data and that they agree to allow the journal to review their data if requested.
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