Volume 33, Issue 1 e13186
Review Article

Therapeutic potential of medicinal plants for the management of scabies

Muhammad Akram

Muhammad Akram

Department of Eastern Medicine, Government College University Faisalabad, Faisalabad, Pakistan

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Muhammad Riaz

Muhammad Riaz

Department of Allied Health Sciences, Sargodha Medical College, University of Sargodha, Sargodha, Pakistan

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Sarwat Noreen

Sarwat Noreen

Department of Physiology, Faculty of Biological Sciences, University of Veterinary and Animal Sciences, Lahore, Pakistan

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Mohammad A. Shariati

Mohammad A. Shariati

Kazakh Research Institute of Processing and Food Industry (Semey branch), Semey, Kazakhstan

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Ghazala Shaheen

Ghazala Shaheen

College of Conventional Medicine, Department of Eastern Medicine, Faculty of Pharmacy and Alternative Medicine, Islamia University of Bahawalpur, Bahawalpur, Pakistan

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Naheed Akhter

Naheed Akhter

College of Allied Health Professional, Government College University Faisalabad, Faisalabad, Pakistan

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Farzana Parveen

Farzana Parveen

Department of Pharmacy, Faculty of Pharmacy and Alternative Medicine, The Islamia University of Bahawalpur, Bahawalpur, Pakistan

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Naheed Akhtar

Naheed Akhtar

Department of Pharmacy, Faculty of Medical and Health Sciences, University of Poonch, Rawalakot, Azad Jammu and Kashmir, Pakistan

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Sadia Zafar

Sadia Zafar

Department of Botany, University of Education (Lahore), Faisalabad, Pakistan

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Aymen Owais Ghauri

Aymen Owais Ghauri

Faculty of Pharmacy, Rayaz College of Eastern Medicine, Jinnah University for Women, Karachi, Pakistan

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Zerfishan Riaz

Zerfishan Riaz

Department of Eastern Medicine, Government College University Faisalabad, Faisalabad, Pakistan

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Fahad S. Khan

Fahad S. Khan

Department of Eastern Medicine, Government College University Faisalabad, Faisalabad, Pakistan

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Shamaila Kausar

Shamaila Kausar

Department of Microbiology, Faculty of Life Sciences, University of Central Punjab, Lahore, Pakistan

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Rida Zainab

Corresponding Author

Rida Zainab

Department of Eastern Medicine, Government College University Faisalabad, Faisalabad, Pakistan

Correspondence

Rida Zainab, Department of Eastern Medicine, Government College University Faisalabad, Faisalabad, Pakistan.

Email: [email protected]

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First published: 12 December 2019
Citations: 20

Abstract

Sarcoptes scabiei (S. scabiei), a parasite mite which causes scabies disease resulting in serious public health concern. The long-term scabies disease can lead to complications such as septicemia, acute post-streptococcal glomerulonephritis, heart disease, and secondary infections. Timely treatment to the affected patients is required to control the disease and get rid of the causative agent. Delayed diagnosis and inappropriate treatment can lead to serious consequences. The most common treatment strategy is the use of allopathic medicines which can immediately relieve the patient but have the drawback of side effects. The safe and cost-effective alternative treatment strategy is the use of medicinal plants which have beneficial therapeutic potential against variety of diseases due to the presence of many bioactive phytoconstituents with no or minimal side effects. For the present review, the published articles describing scabies disease and its phytotherapeutic modalities were searched through different data bases including Google Scholar, PubMed, Medline, and ScienceDirect using the keywords like S. scabiei, prevalence of scabies disease, and phytotherapy of scabies. A large number of medicinal plants, such as Melaleuca alternifolia, Curcuma longa, Azadirachta indica, Rosmarinus officinalis, Capsicum annuum, Cinnamomum camphor, Solanum nigrum, and Eupatorium perfoliatum, have been reviewed for the promising future treatments of scabies. All the studied plants have many bioactive compounds with potential therapeutic effects against scabies and can be utilized for therapeutic purposes for this disease. This literature study has limitations because of the lack of sufficient data due to limited pre-clinical trials in this particular area. This review provides a baseline to explore the therapeutic potential of these medicinal plants against skin diseases. However, extensive studies are required to identify, authenticate, and characterize the bioactive compounds present in these plants which may lead to value addition in pharmaceutical industries providing the cost-effective way of treatment with minimal side effects.

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