Wirksamkeit und Sicherheit nicht-ablativer und ablativer Laser bei Aknenarben: Eine Metaanalyse
Ruonan Ke
Department of Plastic Surgery, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China
Department of Plastic Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, Fujian, China
Search for more papers by this authorBeichen Cai
Department of Plastic Surgery, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China
Department of Plastic Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, Fujian, China
Search for more papers by this authorXuejun Ni
Department of Plastic Surgery, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China
Department of Plastic Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, Fujian, China
Search for more papers by this authorQian Lin
Department of Plastic Surgery, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China
Department of Plastic Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, Fujian, China
Search for more papers by this authorLu Chen
Department of Plastic Surgery, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China
Department of Plastic Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, Fujian, China
Search for more papers by this authorYunjia Xie
Department of Plastic Surgery, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China
Department of Plastic Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, Fujian, China
Search for more papers by this authorXiaofen Wan
Department of Plastic Surgery, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China
Department of Plastic Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, Fujian, China
Search for more papers by this authorCorresponding Author
Xiuying Shan
Department of Plastic Surgery, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China
Department of Plastic Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, Fujian, China
Korrespondenzanschrift
Xiuying Shan, MD, PhD, und Biao Wang, MD, PhD, Department of Plastic Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, Fujian, China.
Email: [email protected]
Search for more papers by this authorCorresponding Author
Biao Wang
Department of Plastic Surgery, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China
Department of Plastic Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, Fujian, China
Korrespondenzanschrift
Xiuying Shan, MD, PhD, und Biao Wang, MD, PhD, Department of Plastic Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, Fujian, China.
Email: [email protected]
Search for more papers by this authorRuonan Ke
Department of Plastic Surgery, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China
Department of Plastic Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, Fujian, China
Search for more papers by this authorBeichen Cai
Department of Plastic Surgery, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China
Department of Plastic Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, Fujian, China
Search for more papers by this authorXuejun Ni
Department of Plastic Surgery, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China
Department of Plastic Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, Fujian, China
Search for more papers by this authorQian Lin
Department of Plastic Surgery, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China
Department of Plastic Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, Fujian, China
Search for more papers by this authorLu Chen
Department of Plastic Surgery, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China
Department of Plastic Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, Fujian, China
Search for more papers by this authorYunjia Xie
Department of Plastic Surgery, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China
Department of Plastic Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, Fujian, China
Search for more papers by this authorXiaofen Wan
Department of Plastic Surgery, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China
Department of Plastic Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, Fujian, China
Search for more papers by this authorCorresponding Author
Xiuying Shan
Department of Plastic Surgery, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China
Department of Plastic Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, Fujian, China
Korrespondenzanschrift
Xiuying Shan, MD, PhD, und Biao Wang, MD, PhD, Department of Plastic Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, Fujian, China.
Email: [email protected]
Search for more papers by this authorCorresponding Author
Biao Wang
Department of Plastic Surgery, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China
Department of Plastic Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, Fujian, China
Korrespondenzanschrift
Xiuying Shan, MD, PhD, und Biao Wang, MD, PhD, Department of Plastic Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, Fujian, China.
Email: [email protected]
Search for more papers by this authorRuonan Ke, Beichen Cai und Xuejun Ni haben gleichermaßen zu dieser Arbeit beigetragen.
Zusammenfassung
Aknenarben beeinträchtigen in erheblichem Maße das physische Erscheinungsbild und das psychische Wohlbefinden. Dies hat die Erforschung verschiedener Therapien, einschließlich ablativer und nicht-ablativer Lasertherapien, angestoßen. Die Debatte über ihre Wirksamkeit und Sicherheit hält an, wodurch die Notwendigkeit einer umfassenden Analyse unterstrichen wird. Die vorliegende Metaanalyse vergleicht die therapeutischen Ergebnisse und Sicherheitsprofile ablativer und nicht-ablativer Laserbehandlungen bei Aknenarben auf der Grundlage einer umfassenden Evaluierung klinischer Studien, die bis März 2023 durchgeführt wurden. Die Auswertung konzentrierte sich auf die klinische Verbesserung, die Patientenzufriedenheit und die Inzidenz behandlungsbedingter Komplikationen. Die Analyse von sieben Studien, die 186 Fälle umfassten, ergab, dass nicht-ablative Laser bei atrophischen Aknenarben wirksamer sind und ein besseres Sicherheitsprofil mit weniger unerwünschten Wirkungen wie verringerten Schmerzen und kürzerer Erythemdauer bieten. Umgekehrt zeigte die ablative Lasertherapie sowohl bei der beobachter- als auch bei der patientenbasierten Auswertung bessere Ergebnisse. Die Erkenntnisse deuten darauf hin, dass zwar beide Lasertypen bei der Milderung von Aknenarben wirksam sind, bei der Wahl zwischen ablativen und nicht-ablativen Lasern jedoch das Gleichgewicht zwischen Wirksamkeit und Sicherheit zu berücksichtigen ist. Die Studie betont die Notwendigkeit weiterer standardisierter Forschung zur Verfeinerung von Laserbehandlungsprotokollen für Aknenarben mit dem Ziel der Ergebnisoptimierung und Risikominimierung.
INTERESSENKONFLIKT
Keiner.
Supporting Information
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