Pediatric cutaneous T-cell post-transplant lymphoproliferative disorder: Case report and review of the literature
Corresponding Author
Thomas S. Rogers
Department of Pathology and Laboratory Medicine, University of Vermont Medical Center, Burlington, Vermont
The Robert Larner MD College of Medicine, The University of Vermont, Burlington, Vermont
Correspondence
Thomas S. Rogers, DO MPH, University of Vermont Medical Center, 111 Colchester Ave, Main Campus EP-1, Burlington, VT 05401.
Email: [email protected]
Search for more papers by this authorLaura McGevna
The Robert Larner MD College of Medicine, The University of Vermont, Burlington, Vermont
Division of Dermatology, University of Vermont Medical Center, Burlington, Vermont
Search for more papers by this authorDeborah L. Cook
Department of Pathology and Laboratory Medicine, University of Vermont Medical Center, Burlington, Vermont
The Robert Larner MD College of Medicine, The University of Vermont, Burlington, Vermont
Search for more papers by this authorCorresponding Author
Thomas S. Rogers
Department of Pathology and Laboratory Medicine, University of Vermont Medical Center, Burlington, Vermont
The Robert Larner MD College of Medicine, The University of Vermont, Burlington, Vermont
Correspondence
Thomas S. Rogers, DO MPH, University of Vermont Medical Center, 111 Colchester Ave, Main Campus EP-1, Burlington, VT 05401.
Email: [email protected]
Search for more papers by this authorLaura McGevna
The Robert Larner MD College of Medicine, The University of Vermont, Burlington, Vermont
Division of Dermatology, University of Vermont Medical Center, Burlington, Vermont
Search for more papers by this authorDeborah L. Cook
Department of Pathology and Laboratory Medicine, University of Vermont Medical Center, Burlington, Vermont
The Robert Larner MD College of Medicine, The University of Vermont, Burlington, Vermont
Search for more papers by this authorAbstract
Post-transplant lymphoproliferative disease (PTLD) is a rare lymphoid and/or plasmacytic proliferation that occurs in the context of immunosuppression because of solid organ transplantation (SOT) and allogeneic hematopoietic stem cell transplantation (HSCT). PTLD is the most common cancer in children who receive a SOT or HSCT, occurring in up to 13% of these patients. The majority of PTLDs are extracutaneous B-cell lymphomas, with only 12% to 14%, representing the T-cell phenotype. PTLDs can involve the skin and behave like an aggressive lymphoma, and are among the most serious and potentially fatal complications of transplantation. Here we present a case report and review of the literature of pediatric cutaneous PTLD.
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