Volume 75, Issue 6 pp. 377-383
Original Article

Cobalt release and complications resulting from the use of dental prostheses

Hiba Al-Imam

Corresponding Author

Hiba Al-Imam

Department of Odontology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 2200 Denmark

Correspondence: Hiba Al-Imam, Department of Odontology, Faculty of Health and Medical Sciences, University of Copenhagen, Nørre Allé 20, DK-2200 Copenhagen, Denmark. Tel: +45 35 32 68 00. E-mail: [email protected]Search for more papers by this author
Ana R. Benetti

Ana R. Benetti

Department of Odontology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 2200 Denmark

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Esben B. Özhayat

Esben B. Özhayat

Department of Odontology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 2200 Denmark

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Anne M. L. Pedersen

Anne M. L. Pedersen

Department of Odontology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 2200 Denmark

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Jeanne D. Johansen

Jeanne D. Johansen

Department of Dermato-Allergology, National Allergy Research Centre, Copenhagen University Hospital, Herlev-Gentofte, 2900 Denmark

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Jacob P. Thyssen

Jacob P. Thyssen

Department of Dermato-Allergology, National Allergy Research Centre, Copenhagen University Hospital, Herlev-Gentofte, 2900 Denmark

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Morten S. Jellesen

Morten S. Jellesen

Department of Mechanical Engineering, Technical University of Denmark, Kgs. Lyngby, 2800 Denmark

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Klaus Gotfredsen

Klaus Gotfredsen

Department of Odontology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 2200 Denmark

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First published: 07 July 2016
Citations: 25
Conflicts of interest: The cobalt spot test was sold to Smarthealth, Phoenix, AZ, USA, and J. P. Thyssen receives annual royalties depending on net sales.
Funding: This scholarship was funded by the Department of Odontology, University of Copenhagen, and by the Research Committee of the Danish Dental Association (FORSKU).

Summary

Background

Cobalt release from dental prostheses has been shown to elicit allergic reactions in cobalt-allergic patients. It is therefore important to investigate whether these prostheses are possible sources of sensitization.

Objectives

To assess (i) cobalt release from dental prostheses and (ii) allergic reactions to components of dental prostheses, and (iii) to investigate the oral mucosa for inflammation 1–5 years after insertion of the prostheses.

Method

Clinical oral examination was conducted in 66 patients with 84 dental prostheses. Cobalt release from 84 functional (used) and 32 non-functional (new) prostheses was investigated with the cobalt spot test. Contact allergy was assessed by patch testing. Smear tests for Candida spp. were performed in patients showing signs of inflammation of the oral mucosa. The prostheses were assessed for biological and technical complications.

Results

None of the functional prostheses released cobalt, whereas this was observed in 24 of 32 non-functional prostheses. None of the patients had contact allergy to cobalt. Of the 66 patients, 11 showed signs of inflammation of the oral mucosa, 2 had oral candidiasis, 16 had ill-fitting prostheses, and all had insufficient oral hygiene.

Conclusions

Dental prostheses released cobalt during the fabrication stages, but not 1–5 years after insertion. No allergic reactions were observed. Signs of inflammation were related to candidiasis, insufficient oral hygiene, and ill-fitting prostheses.

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