Evaluation of the alveolar healing in rats using β-Tricalcium Phosphate associated or not with low power LASER

LQ6ZH ePOSTER CLINICAL RESEARCH – SURGERY

Background: The use of biomaterials to replace autogenous grafts has been the object of study, and has shown promising results.

Aim/Hypothesis: The objective of this study was to verify the effects of β-tricalcium-phosphate and low-power LASER on the alveolar healing.

Materials and Methods: 96 rats (Rattus norvegicus albinus Wistar) were used, being 24 rats for analysis of calcified cuts and 72 rats for analysis of decalcified cuts. All animals underwent extraction of the upper right central incisor and were then divided into 4 groups of 6 animals each: Group CO (Control), Group BTF (Biomaterial), Group LS (low-power LASER), Group BTFL (LASER biomaterial) low power). The animals in the decalcified groups were euthanized at 7.14 and 28 days and the animals in the calcified groups only at 28 days. The jaws were removed and subjected to histological and histometric analysis in the decalcified sections and microcomputerized tomographic analysis (Micro-Ct) in the calcified sections. The data obtained were submitted statistical analysis.

Results: Micro-Ct analysis showed bone tissue formation in all groups, but there was no difference between experimental and control groups. Histometric analysis showed a greater presence of statistically significant neoformed bone tissue in LS at 7 days when compared to other groups.

Conclusions and Clinical Implications: Thus, it was concluded that the low-power LASER accelerated the early stages of the alveolar healing.

Keywords: Low intensity light therapy, Biocompatible materials, Oral Surgery, Biological analysis.