Clinical and histological comparison of collagen matrix and connective tissue graft in the treatment of deep single recessions: experimental study

KWPNO ePOSTER CLINICAL RESEARCH – SURGERY

Background: Coronally advanced flap in combination with connective tissue graft is a golden standard in single gingival recession treatment. Use of connective tissue graft associated with donor site and additional surgical trauma, and can cause complications. Recently collagen resorbable material is suggested for root coverage procedure.

Aim/Hypothesis: The aim of this study was to compare clinical and histological outcomes when used collagen matrix or connective tissue graft in the mini-pig experimental model.

Materials and Methods: Dehiscence defect 3*4 mm were created in root surface in four mini-pigs. In split mouth design, recessions were covered with coronally advanced flap and either with connective tissue graft (control) or with collagen matrix (Mucograft, Geistlich) (test-group). The histological interface between collagen matrix and the root surface was studied and compared with connective tissue graft. Moreover, we assessed the amount and quality of the tissues and clinical result in term of root coverage and recession reduction.

Results: After 4 month, the control-group attained a mean thickness of 2.75 ± 0.80 mm; in the collagen matrix group - 1.50 ± 0.20. The connective tissue graft group attained a mean 75% root coverage, versus 59% in the test-group. Results of the healing in both group were similar. According to histomorphometry the specimens with connective tissue graft consist more vessels and cellular components compare to collagen matrix.

Conclusions and Clinical Implications: Collagen matrix can be used successfully for treatment single deep recessions Miller class I and II. However, connective tissue graft demonstrates more favorable Results

greater width of keratinized tissues and thickness of gingiva.

Keywords: gingival recession, collagen matrix, connective tissue graft, coronally advanced flap, recession coverage