Osseointegration of implants manufactured in Ti-cp or Ti6Al4V or without modified surface laser ablation. Topographic characterization and biomechanical analysis

AR89U ePOSTER CLINICAL RESEARCH – PERI-IMPLANT BIOLOGY

Background: The modifications in the morphological, chemical and physical chemical properties of the implant surface modulate the osseointegration process, this fact has been studied and researched in the scientific literature.

Aim/Hypothesis: To compared the biological and mechanical behavior of the interface formed between bone and implants manufactured in Ti-cp with maCHINAd surface (CPMS) or laser ablation surface (CPLS) with implants manufactured in Ti6Al4V with surfaces maCHINAd (ALLOYMS) or laser ablation (ALLOYLS).

Materials and Methods: Topographic characterization was performed using scanning electron microscopy coupled with X-ray dispersive energy spectroscopy (SEM-EDX) on the implant surfaces prior to experimental surgery. For that, 48 male Wistar rats were randomly given 96 implants with dimension 2x4 mm in their right and left tibiae, one implant of each material (metal) or surface placed in each tibia. In the periods of 14, 21 and 42 days, 8 animals per group were anesthetized and in vivo the biomechanical analysis was performed by means of the removal torque of the implants. The values obtained were taken to the analysis of variance (two-way ANOVA) considering P < 0.05.

Results: The four surfaces analyzed by SEM-EDX showed topographic differences between them. The mean values of CPLS and ALLOYLS were statically superior when compare to CPMS and ALLOYMS at the 14, 21 and 42 days. The mean values ALLOYLS were statically superior when compared to CPLS at the 14, 21 days. At 42 days there was no statically difference, although the mean values of CPLS were higher numerically.

Conclusions and Clinical Implications: It was concluded that with modification by laser ablation accelerated early stages of osseointegration at the implants manufactured in Ti-cp or alloy of Ti6Al4V. It seems like modification by laser ablation provided better results at the implants manufactured in alloy of Ti6Al4V in the early stages of osseointegration.

Acknowledgements: The authors would like to thank Emfils, Novo Colosso, Itu, Brazil to manufacture special implants for experimental study and would like FAPESP (São Paulo State Research Support Foundation) – process number: 2018/22108-1.

Keywords: Dental implants, Topography, Ytterbium laser, Osseointegration, Bone healing