Clinical Implant Dentistry and Related Research

ORIGINAL ARTICLE

Histomorphometric and microtomographic analysis of maxillary sinus augmentation surgeries with and without collagen membrane on the lateral window: A randomized clinical trial

Ramiro Beato Souza DDS, MDSc, PhD

orcid.org/0000-0003-3935-3295

Oral and Maxillofacial Surgeon of Pedro Ernesto University Hospital, Rio de Janeiro State University, Rio de Janeiro, Brazil

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Haimon Diniz Lopes Alves DDS, MDSc, PhD,

Haimon Diniz Lopes Alves DDS, MDSc, PhD

Physics Department, Rio de Janeiro State University, Rio de Janeiro, Brazil

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Luciano Santos Oliveira DDS, MDSc, PhD,

Luciano Santos Oliveira DDS, MDSc, PhD

Department of Implantology, Catholic University of Rio de Janeiro, Rio de Janeiro, Brazil

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Fabio Ramoa Pires DDS, MDSc, PhD,

Fabio Ramoa Pires DDS, MDSc, PhD

Oral Pathology, Dental School, Rio de Janeiro State University, Brazil, Rio de Janeiro State University, Rio de Janeiro, Brazil

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Guaracilei Maciel Vidigal Jr DDS, MDSc, PhD,

Guaracilei Maciel Vidigal Jr DDS, MDSc, PhD

orcid.org/0000-0002-4514-6906

Department of Periodontology, Rio de Janeiro State University, Rio de Janeiro, Brazil

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Ricardo Guimaraes Fischer MD, DDS, MDSc, PhD,

Corresponding Author

Ricardo Guimaraes Fischer MD, DDS, MDSc, PhD

[email protected]

Department of Periodontology, Rio de Janeiro State University, Rio de Janeiro, Brazil

Correspondence

Ricardo Guimaraes Fischer, Department of Periodontology, Rio de Janeiro State University, Boulevard 28 de Setembro, 157, CEP 20551-030 Rio de Janeiro, Brazil.

Email: [email protected]

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Ramiro Beato Souza DDS, MDSc, PhD,

Ramiro Beato Souza DDS, MDSc, PhD

orcid.org/0000-0003-3935-3295

Oral and Maxillofacial Surgeon of Pedro Ernesto University Hospital, Rio de Janeiro State University, Rio de Janeiro, Brazil

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Haimon Diniz Lopes Alves DDS, MDSc, PhD,

Haimon Diniz Lopes Alves DDS, MDSc, PhD

Physics Department, Rio de Janeiro State University, Rio de Janeiro, Brazil

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Luciano Santos Oliveira DDS, MDSc, PhD,

Luciano Santos Oliveira DDS, MDSc, PhD

Department of Implantology, Catholic University of Rio de Janeiro, Rio de Janeiro, Brazil

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Fabio Ramoa Pires DDS, MDSc, PhD,

Fabio Ramoa Pires DDS, MDSc, PhD

Oral Pathology, Dental School, Rio de Janeiro State University, Brazil, Rio de Janeiro State University, Rio de Janeiro, Brazil

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Guaracilei Maciel Vidigal Jr DDS, MDSc, PhD,

Guaracilei Maciel Vidigal Jr DDS, MDSc, PhD

orcid.org/0000-0002-4514-6906

Department of Periodontology, Rio de Janeiro State University, Rio de Janeiro, Brazil

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Ricardo Guimaraes Fischer MD, DDS, MDSc, PhD,

Corresponding Author

Ricardo Guimaraes Fischer MD, DDS, MDSc, PhD

[email protected]

Department of Periodontology, Rio de Janeiro State University, Rio de Janeiro, Brazil

Correspondence

Ricardo Guimaraes Fischer, Department of Periodontology, Rio de Janeiro State University, Boulevard 28 de Setembro, 157, CEP 20551-030 Rio de Janeiro, Brazil.

Email: [email protected]

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First published: 21 June 2024

https://doi.org/10.1111/cid.13331

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Abstract

Objective

To evaluate the histomorphometric and computerized microtomographic (Micro-CT) analysis of the regenerated bone tissue from maxillary sinus augmentation surgery, with and without using the collagen membrane on the external osteotomy window.

Materials and Methods

Twelve patients were selected for this prospective, controlled, and randomized study. The patients were submitted to bilateral maxillary sinus surgery in a split-mouth design. On the test side, the maxillary sinus augmentation procedure included using Geistlich Bio-Oss® and a Geistlich Bio-Gide® collagen membrane covering the lateral osteotomy window. On the control side, only Geistlich Bio-Oss® was used without the presence of the membrane. After 6 months, the surgeries for implant installation were performed. In this surgical phase, specimens of the regenerated tissue were collected for histological and Micro-CT analysis.

Results

In the histomorphometric evaluation, the mean (±SD) percentages of newly formed bone were 43.9% (±11.5) and 40.8% (±8.9) in the test and control groups, respectively. The corresponding values of the Micro-CT analysis were 36.6% (±3.4) and 37.2% (±4.7) in the test and control groups, respectively. There was no statistically significant difference between the test and control groups in the two methods. In addition, there was no statistically significant difference between the mean percentage of biomaterial remaining between the test and control groups. However, the mean percentage of newly formed bone was significantly higher and the mean percentage of remaining biomaterial was significantly lower in the histomorphometric analysis compared to the values obtained through microtomography.

Conclusion

The additional use of collagen membranes in maxillary sinus surgery does not offer advantages in newly formed bone.

CONFLICT OF INTEREST STATEMENT

The authors declare no conflict of interest.

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Volume26, Issue4

August 2024

Pages 787-794

Histomorphometric and microtomographic analysis of maxillary sinus augmentation surgeries with and without collagen membrane on the lateral window: A randomized clinical trial

Abstract

Objective

Materials and Methods

Results

Conclusion

CONFLICT OF INTEREST STATEMENT

REFERENCES

References

Information

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