Dear Editor, Fungi must meet four criteria to infect humans: growth at human body temperatures, penetration of surface barriers, lysis and absorption of tissue, and resistance to immune defences.1 Despite the superficial localization of dermatophytosis, the host–fungus relationship in dermatophytosis is still poorly elucidated.2 After adherence to the skin surface, penetration of surface barriers is a requirement for dermatophytosis. Trichophyton rubrum is the most common anthropophilic dermatophyte, and was isolated from the scutula of a 26-year-old immunocompetent man with scrotal favus. This colour-enhanced scanning electron microscopy image is of the scutula, demonstrating T. rubrum penetrating into the inner epidermis in vivo. For other images, see Supplementary Material S1 (Supporting Information).
Supplementary Material S1 Clinical picture, and direct microscopy, transmission electron microscopy (TEM) and scanning electron (SEM) microscopy images of the Trichophyton rubrum penetration.
Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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