Volume 109, Issue 11 pp. 2302-2308
REGULAR ARTICLE

Multicentre Spanish study found no incidences of viral transmission in infants born to mothers with COVID-19

Miguel A. Marín Gabriel

Corresponding Author

Miguel A. Marín Gabriel

Department of Neonatology, Puerta de Hierro-Majadahonda University Hospital, Madrid, Spain

Pediatric Department, Autónoma University, Madrid, Spain

Correspondence

Miguel Ángel Marín Gabriel, Department of Pediatrics, Puerta de Hierro-Majadahonda University Hospital, 1 Manuel de Falla Street, Majadahonda, Madrid, 28221, Spain.

Email: [email protected]

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Irene Cuadrado

Irene Cuadrado

Department of Neonatology, Getafe University Hospital, Getafe, Spain

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Blanca Álvarez Fernández

Blanca Álvarez Fernández

Department of Neonatology, Rey Juan Carlos University Hospital, Móstoles, Spain

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Ersilia González Carrasco

Ersilia González Carrasco

Department of Neonatology, Severo Ochoa University Hospital, Leganés, Spain

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Clara Alonso Díaz

Clara Alonso Díaz

Department of Neonatology, 12 de Octubre University Hospital, Madrid, Spain

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Isabel Llana Martín

Isabel Llana Martín

Department of Neonatology, HM Puerta del Sur University Hospital, Móstoles, Spain

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Laura Sánchez

Laura Sánchez

Department of Neonatology, La Paz University Hospital, Madrid, Spain

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Cristina Olivas

Cristina Olivas

Department of Neonatology, Príncipe de Asturias University Hospital, Alcalá de Henares, Spain

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Susana de las Heras

Susana de las Heras

Department of Neonatology, Fuenlabrada University Hospital, Madrid, Spain

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Enrique Criado

Enrique Criado

Department of Neonatology, Clínico San Carlos University Hospital, Madrid, Spain

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on behalf of the Neo-COVID-19 Research Group

the Neo-COVID-19 Research Group

The members of Neo-COVID-19 Research Group are listed in Acknowledgement section

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First published: 10 July 2020
Citations: 30

Abstract

Aim

Our aim was to describe the clinical features of mothers infected with COVID-19 and examine any potential vertical mother to newborn transmission. We also assessed how effective the discharge recommendations were in preventing transmission during the first month of life.

Methods

This multicentre descriptive study involved 16 Spanish hospitals. We reviewed the medical records of 42 pregnant women diagnosed with COVID-19 from March 13, 2020, to March 29, 2020, when they were in their third trimester of pregnancy. They and their newborn infants were monitored until the infant was 1 month old.

Results

Over half (52.4%) of the women had a vaginal delivery. The initial clinical symptoms were coughing (66.6%) and fever (59.5%), and one mother died due to thrombo-embolic events. We admitted 37 newborn infants to the neonatal unit (88%), and 28 were then admitted to intermediate care for organisational virus-related reasons. No infants died, and no vertical transmission was detected during hospitalisation or follow-up. Only six were exclusively breastfed at discharge.

Conclusion

There was no evidence of COVID-19 transmission in any of the infants born to COVID-19 mothers, and the post-discharge advice seemed effective. The measures to avoid transmission appeared to reduce exclusive breastfeeding at discharge.

CONFLICT OF INTEREST

The authors have no conflicts of interest to declare.

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