Volume 108, Issue 5 pp. 961-966
Regular Article

More severe intellectual disability found in teenagers compared to younger children with Down syndrome

Ulrika Wester Oxelgren

Corresponding Author

Ulrika Wester Oxelgren

Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden

Correspondence

Ulrika Wester Oxelgren, Department of Women's and Children's Health, University Children's Hospital, S-751 85 Uppsala, Sweden.

Tel: +46 18 611 68 39 ¦

Email: [email protected]

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Åsa Myrelid

Åsa Myrelid

Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden

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Göran Annerén

Göran Annerén

Department of Immunology, Genetics, and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden

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Joakim Westerlund

Joakim Westerlund

Department of Psychology, Stockholm University, Stockholm, Sweden

Gillberg Neuropsychiatry Centre, Department of Neuroscience and Physiology, Gothenburg University, Gothenburg, Sweden

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Jan Gustafsson

Jan Gustafsson

Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden

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Elisabeth Fernell

Elisabeth Fernell

Gillberg Neuropsychiatry Centre, Department of Neuroscience and Physiology, Gothenburg University, Gothenburg, Sweden

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First published: 29 October 2018
Citations: 7

Abstract

Aim

We investigated the severities and profiles of intellectual disability (ID) in a population-based group of children with Down syndrome and related the findings to coexisting autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD).

Methods

There were about 100 children with Down syndrome living in Uppsala County, Sweden, at the time of the study who all received medical services from the same specialist outpatient clinic. The 60 children (68% male) were aged 5–17 years at inclusion: 41 were assessed within the study and 19 had test results from previous assessments, performed within three years before inclusion. We compared two age groups: 5–12 and 13–18 years old.

Results

Of the 60 children, 49 were assessed with a cognitive test and the 11 children who could not participate in formal tests had clinical assessments. Mild ID was found in 9% of the older children and in 35% of the younger children. Severe ID was found in 91% of the older children and 65% of the younger children. Verbal and nonverbal domains did not differ.

Conclusion

Intellectual level was lower in the older children and patients with Down syndrome need to be followed during childhood with regard to their ID levels.

Conflict of interest

The authors have no conflict of interests to declare.

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